Approval Year
| Substance Class |
Nucleic Acid
Created
by
admin
on
Edited
Sat Dec 16 15:52:44 UTC 2023
by
admin
on
Sat Dec 16 15:52:44 UTC 2023
|
| Nucleic Acid Type | OLIGONUCLEOTIDE |
| Nucleic Acid Subtype | |
| Record UNII |
2H1PA8H1EN
|
| Record Status |
Validated (UNII)
|
| Record Version |
|
-
Download
| Name | Type | Language | ||
|---|---|---|---|---|
|
Official Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English | ||
|
Common Name | English |
| Classification Tree | Code System | Code | ||
|---|---|---|---|---|
|
WHO-VATC |
QS01LA03
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
||
|
NCI_THESAURUS |
C1742
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
||
|
NDF-RT |
N0000178292
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
||
|
WHO-ATC |
S01LA03
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
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|
EMA ASSESSMENT REPORTS |
MACUGEN (AUTHORIZED: WET MACULAR DEGENERATION)
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
| Code System | Code | Type | Description | ||
|---|---|---|---|---|---|
|
C90657
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
N0000170810
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | Aptamers, Nucleotide [Chemical/Ingredient] | ||
|
8215
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
498509
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | RxNorm | ||
|
N0000011393
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | Oligonucleotides [Chemical/Ingredient] | ||
|
CHEMBL2108752
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
6836
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
DB04895
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
C495058
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
PEGAPTANIB
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
4905
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
SUB25196
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY | |||
|
2H1PA8H1EN
Created by
admin on Sat Dec 16 15:52:44 UTC 2023 , Edited by admin on Sat Dec 16 15:52:44 UTC 2023
|
PRIMARY |
| Sugar | Site Range | Site Count |
|---|---|---|
| D-Ribose (RNA) | 1_4-1_5 | 2 / 28 |
| Deoxyribose (DNA) | 1_28 | 1 / 28 |
| 2'-O-Methyl-Ribose | 1_2-1_3;1_8-1_9;1_11-1_13;1_15;1_19;1_21;1_23;1_27 | 12 / 28 |
| 2'-Fluoro-Ribose | 1_1;1_6-1_7;1_10;1_14;1_16-1_18;1_20;1_22;1_24-1_26 | 13 / 28 |
| Linkage | Site Range | Site Count |
|---|---|---|
| Phosphate | 1_1-1_27 | 27 / 27 |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
TARGET -> INHIBITOR |
| Related Record | Type | Details | ||
|---|---|---|---|---|
|
|
ACTIVE MOIETY |
Structural Modifications
| Modification Type | Location Site | Location Type | Residue Modified | Extent | Fragment Name | Fragment Approval |
|---|---|---|---|---|---|---|
| NUCLEOTIDE SUBSTITUTION | [1_28] | THYMIDINE 3'-MONOPHOSPHATE | Q84LAH3NDH | |||
| PEGYLATION | [1_1] | SITE_SPECIFIC | PEGAPTANIB, PEGYLATED 2'-DEOXY-2'-FLUOROURIDINE 5'-MONOPHOSPHATE- | 0E3EGS14RZ |