Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C4H11NO |
| Molecular Weight | 89.1362 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CN(C)CCO
InChI
InChIKey=UEEJHVSXFDXPFK-UHFFFAOYSA-N
InChI=1S/C4H11NO/c1-5(2)3-4-6/h6H,3-4H2,1-2H3
| Molecular Formula | C4H11NO |
| Molecular Weight | 89.1362 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
DEANOL is an inactive component of CERAVE® hydrocortisone anti-itch cream, which is used for temporarily relieve itching associated with minor skin irritations, inflammation, and rashes due to eczema, soaps, detergents, cosmetics, seborrheic dermatitis, psoriasis. DEANOL is also used as a food additive.
Approval Year
Doses
| Dose | Population | Adverse events |
|---|---|---|
0.1 % single, topical Highest studied dose Dose: 0.1 % Route: topical Route: single Dose: 0.1 % Sources: |
healthy |
|
6000 mg 1 times / day multiple, oral Highest studied dose Dose: 6000 mg, 1 times / day Route: oral Route: multiple Dose: 6000 mg, 1 times / day Sources: |
unhealthy |
PubMed
| Title | Date | PubMed |
|---|---|---|
| Release of DNA from polyelectrolyte multilayers fabricated using 'charge-shifting' cationic polymers: tunable temporal control and sequential, multi-agent release. | 2010-11-20 |
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| In vitro cytotoxicity of benzopyranone derivatives with basic side chain against human lung cell lines. | 2010-11 |
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| Reduced dimethylaminoethanol in [(18)F]fluoromethylcholine: an important step towards enhanced tumour visualization. | 2010-11 |
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| Novel pathway to synthesize unsymmetrical 2,3,9,10,16,17,23-heptakis(alkoxyl)-24-mono(dimethylaminoalkoxyl)phthalocyanines. | 2010-10-04 |
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| Novel tricyclic pyrazole BRAF inhibitors with imidazole or furan central scaffolds. | 2010-09-15 |
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| Chloridotris[μ(2)-2-(dimethyl-amino)-ethano-lato]-μ(3)-hydroxido-tri-μ(2)-trifluoro-acetato-tetra-copper(II) tetra-hydro-furan solvate. | 2010-06-18 |
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| The choC gene encoding a putative phospholipid methyltransferase is essential for growth and development in Aspergillus nidulans. | 2010-06 |
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| Structural characterization and stability of dimethylaminoethanol and dimethylaminoethanol bitartrate for possible use in cosmetic firming. | 2010-05-13 |
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| Application of high performance liquid chromatography coupled to on-line solid-phase extraction-nuclear magnetic resonance spectroscopy for the analysis of degradation products of V-class nerve agents and nitrogen mustard. | 2010-04-23 |
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| Efficient automated one-step synthesis of 2-[18F]fluoroethylcholine for clinical imaging: optimized reaction conditions and improved quality controls of different synthetic approaches. | 2010-04 |
|
| First efficient synthesis of fluorinated glycidic esters from ketones. | 2010-02-19 |
|
| Mesotherapy - The french connection. | 2010-01 |
|
| In vivo skin effects of a dimethylaminoethanol (DMAE) based formulation. | 2009-12 |
|
| Effects of dimethylaminoethanol pyroglutamate (DMAE p-Glu) against memory deficits induced by scopolamine: evidence from preclinical and clinical studies. | 2009-12 |
|
| The pentameric vertex proteins are necessary for the icosahedral carboxysome shell to function as a CO2 leakage barrier. | 2009-10-21 |
|
| Mitochondrial 2,4-dienoyl-CoA reductase deficiency in mice results in severe hypoglycemia with stress intolerance and unimpaired ketogenesis. | 2009-07 |
|
| Quantitative determination of dimethylaminoethanol in cosmetic formulations by nuclear magnetic resonance spectroscopy. | 2009-02-11 |
|
| Bis[N-(2-hydroxy-ethyl)-N-methyl-glycinato]copper(II). | 2008-11-22 |
|
| Strong intramolecular Si-N interactions in the chlorosilanes Cl3-nHnSiOCH2CH2NMe2 (n = 1-3). | 2008-11-17 |
|
| Organocadmium aminoalcoholates: synthesis, structure, and materials chemistry. | 2008-10-20 |
|
| Synthesis, cytotoxicity, DNA interaction, and topoisomerase II inhibition properties of novel indeno[2,1-c]quinolin-7-one and indeno[1,2-c]isoquinolin-5,11-dione derivatives. | 2008-06-26 |
|
| Role of the ancillary ligand N,N-dimethylaminoethanol in the sensitization of Eu(III) and Tb(III) luminescence in dimeric beta-diketonates. | 2008-04-24 |
|
| Experimental and theoretical investigation into the correlation between mass and ion mobility for choline and other ammonium cations in N2. | 2008-03-15 |
|
| Fully automated [18F]fluorocholine synthesis in the TracerLab MX FDG Coincidence synthesizer. | 2008-02 |
|
| Randomised, placebo-controlled, double-blind, split-face study on the clinical efficacy of Tricutan on skin firmness. | 2007-11 |
|
| Dimethylaminoethanol affects the viability of human cultured fibroblasts. | 2007-10-18 |
|
| Mannosylated poly(ethylene oxide)-b-poly(epsilon-caprolactone) diblock copolymers: synthesis, characterization, and interaction with a bacterial lectin. | 2007-09 |
|
| A new design strategy for dispersion stabilization of Ni particles based on the surface acid and base properties of Ni particles. | 2007-08-15 |
|
| Synthesis and characterization of succinylcholine-d18 and succinylmonocholine-d3 designed for simultaneous use as internal standards in mass spectrometric analyses. | 2007-07 |
|
| Improved automated synthesis of [18F]fluoroethylcholine as a radiotracer for cancer imaging. | 2007-05-01 |
|
| The antiwrinkle effect of topical concentrated 2-dimethylaminoethanol involves a vacuolar cytopathology. | 2007-03 |
|
| Self-assembly of the unique heterotrimetallic Cu/Co/M complexes possessing triangular antiferromagnetic {Cu2CoPb}2 and linear ferromagnetic {Cu2CoCd2} cores. | 2007-02-07 |
|
| Synthesis of isostructural cage complexes of copper with cobalt and nickel for deposition of mixed ceramic oxide materials. | 2006-12-25 |
|
| C-terminal sequencing method for proteins in polyacrylamide gel by the reaction of acetic anhydride. | 2006-04 |
|
| The evolution of senescence and post-reproductive lifespan in guppies (Poecilia reticulata). | 2006-01 |
|
| The role of dimethylaminoethanol in cosmetic dermatology. | 2005 |
|
| [Fluorescent-labeled lipophilic analogues of serotonin, dopamine, and acetylcholine: synthesis, mass spectrometry, and biological activity]. | 2004-11-26 |
|
| Phosphazene-based ionic liquids: synthesis, temperature-dependent viscosity, and effect as additives in water lubrication of silicon nitride ceramics. | 2004-08-23 |
|
| [11C]Choline as a PET biomarker for assessment of prostate cancer tumor models. | 2004-06-01 |
|
| Highly efficient automated synthesis of [(11)C]choline for multi dose utilization. | 2004-06 |
|
| Copper (II)-mediated arylation with aryl boronic acids for the N-derivatization of pyrazole libraries. | 2004-05-11 |
|
| Reactivity and molecular recognition: amine methylation by an introverted ester. | 2003-12-03 |
|
| The sea urchin embryo as a model for mammalian developmental neurotoxicity: ontogenesis of the high-affinity choline transporter and its role in cholinergic trophic activity. | 2003-11 |
|
| Efficacy of dimethylaminoethanol (DMAE) containing vitamin-mineral drug combination on EEG patterns in the presence of different emotional states. | 2003-05-30 |
|
| Water-soluble biodegradable cationic polyphosphazenes for gene delivery. | 2003-05-20 |
|
| [18F]fluoromethyl triflate, a novel and reactive [18F]fluoromethylating agent: preparation and application to the on-column preparation of [18F]fluorocholine. | 2002-09 |
|
| Split face study on the cutaneous tensile effect of 2-dimethylaminoethanol (deanol) gel. | 2002-08 |
|
| Improved method for the quality assurance of [C-11]choline. | 2002-04 |
|
| Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro. | 2002-04 |
|
| Studies of the side chain cleavage of deramciclane in rats with radiolabelled compounds. | 2002-03 |
Patents
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 17:33:38 GMT 2025
by
admin
on
Mon Mar 31 17:33:38 GMT 2025
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| Record UNII |
2N6K9DRA24
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| Record Status |
Validated (UNII)
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| Record Version |
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NCI_THESAURUS |
C265
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DSLD |
1303 (Number of products:461)
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WHO-VATC |
QN06BX04
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WHO-ATC |
N06BX04
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2652
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100000091061
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1329
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2N6K9DRA24
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D003642
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7902
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SUB13534MIG
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3116
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108-01-0
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787
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DTXSID2020505
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SUB13536MIG
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ALTERNATIVE | |||
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DIMETHYLETHANOLAMINE
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271436
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DB13352
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C72733
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2N6K9DRA24
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m4115
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203-542-8
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DEANOL
Created by
admin on Mon Mar 31 17:33:38 GMT 2025 , Edited by admin on Mon Mar 31 17:33:38 GMT 2025
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PRIMARY | Dimethylethanolamine is used in the preparation of water-reducible coating formulations. Government regulations covering the amount of organic solvent allowable in the air have spurred a search for emission control procedures. One of the most promising is the replacement of the organic solvent by water. The resins used in coating formulations are not water soluble, but can be made so by reacting them with the amine. |
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ACTIVE MOIETY |
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