Vonsetamig

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 00:15:36 GMT 2025` Edited by `admin` on `Wed Apr 02 00:15:36 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	30WLL6DR9O
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Vonsetamig

Official Name

English

Immunoglobulin G4 [103-cysteine,108-cysteine,233-proline,238-proline,239-valine,240-alanine,de-241-glycine], anti-(human B-cell maturation antigen) (human monoclonal REGN5459 ?4-chain), disulfide with human monoclonal REGN5459 ?-chain, (231?230?),(234?23

Preferred Name

English

vonsetamig [INN]

Common Name

English

Immunoglobulin G4-kappa, anti-[Homo sapiens TNFRSF17 (TNF receptor superfamily member 17, BCMA, TNFRSF13A, CD269) and CD3E (CD3 epsilon)], Homo sapiens monoclonal antibody, bispecific, bivalent

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C199130

Created by admin on Wed Apr 02 00:15:36 GMT 2025 , Edited by admin on Wed Apr 02 00:15:36 GMT 2025

PRIMARY

FDA UNII

30WLL6DR9O

Created by admin on Wed Apr 02 00:15:36 GMT 2025 , Edited by admin on Wed Apr 02 00:15:36 GMT 2025

PRIMARY

INN

12494

Created by admin on Wed Apr 02 00:15:36 GMT 2025 , Edited by admin on Wed Apr 02 00:15:36 GMT 2025

PRIMARY

CAS

2408319-33-3

Created by admin on Wed Apr 02 00:15:36 GMT 2025 , Edited by admin on Wed Apr 02 00:15:36 GMT 2025

PRIMARY

SMS_ID

300000014260

Created by admin on Wed Apr 02 00:15:36 GMT 2025 , Edited by admin on Wed Apr 02 00:15:36 GMT 2025

PRIMARY

From	To
1_22	1_96
1_103	1_108
1_139	3_215
1_152	1_208
1_231	2_230
1_234	2_233
1_265	1_325
1_371	1_429
2_22	2_96
2_138	4_215
2_151	2_207
2_264	2_324
2_370	2_428
3_23	3_88
3_135	3_195
4_23	4_88
4_135	4_195

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_301
N	2_300

Related Record Type Details


					ZLW14X2D30

CD3

TARGET -> ACTIVATOR

Amount:


					PK6VHJAIBD

TUMOR NECROSIS FACTOR RECEPTOR SUPERFAMILY MEMBER 17

TARGET->LIGAND

Amount:

Related Record Type Details


					30WLL6DR9O

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL