Trastuzumab Envedotin

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 21:17:31 GMT 2025` Edited by `admin` on `Tue Apr 01 21:17:31 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY CONJUGATE
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	37DMF82G1F
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Trastuzumab Envedotin

Official Name

English

DP-303C

Preferred Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (receptor tyrosine-protein kinase erbB-2, epidermal growth factor receptor 2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody, conjugated at glutaminyl residues to monomethyla

Common Name

English

Immunoglobulin G1, anti-(human epidermal growth factor receptor HER2) (human-Mus musculus monoclonal DP001 ?1-chain), disulfide with human-Mus musculus monoclonal DP001 ?-chain, dimer, 298,298?-diamide with N-[[[4-[[N-[2-[2-[2-(2-aminoethoxy)ethoxy]ethox

Common Name

English

trastuzumab envedotin [INN]

Common Name

English

H-gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV3-66*01 (81.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (217) (121-218), hinge 1-

Common Name

English

DP303C

Code

English

Code System Code Type Description

SMS_ID

300000054738