U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

1998
123
Substance Class Protein
Created
by admin
on Mon Mar 31 20:46:00 GMT 2025
Edited
by admin
on Mon Mar 31 20:46:00 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin HUMANIZED MOUSE
Sequence Type COMPLETE
Record UNII
P188ANX8CK
Record Status FAILED
Record Version
  • Download
Related Record Type
ALTERNATIVE DEFINITION for [TRASTUZUMAB]
Alternative Definition
Name Type Language
TRASTUZUMAB
EMA EPAR   INN   MART.   MI   USAN   VANDF   WHO-DD  
USAN   INN  
Official Name English
TRASTUZUMAB, LICENSE HOLDER UNSPECIFIED
Preferred Name English
RHUMABHER2
Code English
RO0452317
Code English
R-597
Code English
TRASTUZUMAB [JAN]
Common Name English
trastuzumab [INN]
Common Name English
4D5V8
Code English
SYD-977
Code English
TRASTUZUMAB [USAN]
Common Name English
IMMUNOGLOBULIN G1 (HUMAN-MOUSE MONOCLONAL RHUMAB HER2(SUB .GAMMA.1)-CHAIN ANTIHUMAN P185(SUP C-ERBB2) RECEPTOR), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL RHUMAB HER2 LIGHT CHAIN, DIMER
Common Name English
Trastuzumab [WHO-DD]
Common Name English
TRASTUZUMAB [MI]
Common Name English
IMMUNOGLOBULIN G 1 (HUMAN-MOUSE MONOCLONAL RHUMAB HER2(SUB .GAMMA.1)-CHAIN ANTIHUMAN P185(SUP C-ERBB2) RECEPTOR), DISULPHIDE WITH HUMAN-MOUSE MONOCLONAL RHUMAB HER2 LIGHT CHAIN, DIMER
Common Name English
IMMUNOGLOBULIN G1 (HUMAN-MOUSE MONOCLONAL RHUMAB HER2(SUB .GAMMA.1)-CHAIN ANTIHUMAN P185(SUP C-ERBB2) RECEPTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL RHUMAB HER2 LIGHT CHAIN, DIMER
Common Name English
TRASTUZUMAB [PURPLE BOOK CDER]
Common Name English
TRASTUZUMAB [EMA EPAR]
Common Name English
IMMUNOGLOBULIN G 1 (HUMAN-MOUSE MONOCLONAL RHUMAB HER2(SUB .GAMMA.1)-CHAIN ANTIHUMAN P185(SUP C-ERBB2) RECEPTOR), DISULFIDE WITH HUMAN-MOUSE MONOCLONAL RHUMAB HER2 LIGHT CHAIN, DIMER
Common Name English
TRASTUZUMAB [VANDF]
Common Name English
TRASTUZUMAB [MART.]
Common Name English
RHUMAB HER2
Code English
SYD977
Code English
RO-0452317
Code English
Classification Tree Code System Code
NDF-RT N0000020008
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
NDF-RT N0000175661
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
NDF-RT N0000020008
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
LIVERTOX NBK548559
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
EMA ASSESSMENT REPORTS HERCEPTIN (AUTHORIZED: STOMACH NEOPLASMS)
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
WHO-VATC QL01XC03
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
FDA ORPHAN DRUG 292409
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
FDA ORPHAN DRUG 129399
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
WHO-ATC L01XC03
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
NCI_THESAURUS C155711
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
Code System Code Type Description
USAN
II-48
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
IUPHAR
5082
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
CAS
180288-69-1
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
RXCUI
2107051
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
ALTERNATIVE
RXCUI
224905
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY RxNorm
LACTMED
Trastuzumab
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
MESH
C112748
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
MERCK INDEX
m11006
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY Merck Index
WIKIPEDIA
TRASTUZUMAB
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
RXCUI
2174802
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
ALTERNATIVE
SMS_ID
100000089314
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
INN
7637
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
DAILYMED
P188ANX8CK
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
FDA UNII
P188ANX8CK
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
NCI_THESAURUS
C1647
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
ChEMBL
CHEMBL1201585
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
HSDB
8142
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
EVMPD
SUB12612MIG
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
DRUG CENTRAL
4979
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
RXCUI
2289225
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
ALTERNATIVE
RXCUI
2103478
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
ALTERNATIVE
RXCUI
2280730
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
ALTERNATIVE
DRUG BANK
DB00072
Created by admin on Mon Mar 31 20:46:00 GMT 2025 , Edited by admin on Mon Mar 31 20:46:00 GMT 2025
PRIMARY
From To
1_22 1_96
1_147 1_203
1_223 3_214
1_229 2_229
1_232 2_232
1_264 1_324
1_370 1_428
2_22 2_96
2_147 2_203
2_223 4_214
2_264 2_324
2_370 2_428
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 1_300
N 2_300
Related Record Type Details
Trastuzumab brengitecan
CONJUGATE -> PARENT
Trastuzumab mafodotin
CONJUGATE->CONJUGATE COMPONENT
Trastuzumab Vedotin
CONJUGATE->CONJUGATE COMPONENT
TRASTUZUMAB-ZZXF
SUB_CONCEPT->SUBSTANCE
Trastuzumab-STRF
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB (HERCEPTIN)
INNOVATOR->PARENT
TRASTUZUMAB-PKRB
BIOSIMILAR -> PARENT
ZIRCONIUM ZR-89 TRASTUZUMAB
LABELED -> NON-LABELED
RECEPTOR TYROSINE-PROTEIN KINASE ERBB-2
TARGET -> INHIBITOR
HIGH AFFINITY IMMUNOGLOBULIN GAMMA FC RECEPTOR I
TARGET -> AGONIST
TRASTUZUMAB EMTANSINE
CONJUGATE -> PARENT
Trastuzumab Envedotin
CONJUGATE -> PARENT
DMB-3111
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB-QYYP
BIOSIMILAR -> PARENT
Trastuzumab-STRF
BIOSIMILAR -> PARENT
EG-12014
BIOSIMILAR -> PARENT
TRASTUZUMAB-PKRB
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB-ANNS
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB-DKST
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB (HERCEPTIN)
SUB_CONCEPT->SUBSTANCE
EG-12014
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB-DTTB
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB-DKST
BIOSIMILAR -> PARENT
TRASTUZUMAB-QYYP
SUB_CONCEPT->SUBSTANCE
TRASTUZUMAB CORIXETAN THORIUM TH-227
CONJUGATE -> PARENT
TRASTUZUMAB-ANNS
BIOSIMILAR -> PARENT
Trastuzumab-OYSK
SUB_CONCEPT->SUBSTANCE
Related Record Type Details
TRASTUZUMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID REMOVAL [1_450] [2_450] C-TERMINUS Amount: LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:ESTIMATED(SDS-PAGE) CHEMICAL
NIH
NCATS
PRIVACY NOTICE
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DISCLAIMER
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