U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Structurally Diverse
Created
by admin
on Wed Apr 02 16:29:47 GMT 2025
Edited
by admin
on Wed Apr 02 16:29:47 GMT 2025
Source Materials Class ORGANISM
Source Materials Type RECOMBINANT VIRUS
Source Materials State LIVE NON-REPLICATING GENETICALLY MODIFIED
Organism Family Adenoviridae
Organism Genus Mastadenovirus
Organism Species human mastadenovirus c
Infraspecific Type RECOMBINANT VECTOR
Infraspecific Name Helper-dependent adenovirus (HDAd) serotype 5 vector expressing human interleukin-1 receptor antagonist (IL-1Ra) gene controlled by a NF-?B-inducible promoter
Part whole
Record UNII
3KJ43QLJ8F
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
FX-201
Preferred Name English
Enekinragene Inzadenovec
INN   USAN  
Official Name English
recombinant, non-replicating adenovirus type 5 (Ad5) vector encoding codon-optimised human interleukin 1 receptor antagonist (IL-1Ra) under the control of an engineered nuclear factor kappa B (NF-?B) inducible promoter composed of five conserved NF-?B bi
Common Name English
enekinragene inzadenovec [INN]
Common Name English
ENEKINRAGENE INZADENOVEC [USAN]
Common Name English
GQ-203
Code English
FX201
Code English
PCRX-201
Code English
Humantakinogene hadenovec
Common Name English
GQ203
Code English
Code System Code Type Description
USAN
MN-17
Created by admin on Wed Apr 02 16:29:47 GMT 2025 , Edited by admin on Wed Apr 02 16:29:47 GMT 2025
PRIMARY
NCI_THESAURUS
C190333
Created by admin on Wed Apr 02 16:29:47 GMT 2025 , Edited by admin on Wed Apr 02 16:29:47 GMT 2025
PRIMARY
FDA UNII
3KJ43QLJ8F
Created by admin on Wed Apr 02 16:29:47 GMT 2025 , Edited by admin on Wed Apr 02 16:29:47 GMT 2025
PRIMARY
CAS
2618581-50-1
Created by admin on Wed Apr 02 16:29:47 GMT 2025 , Edited by admin on Wed Apr 02 16:29:47 GMT 2025
PRIMARY
SMS_ID
300000047312
Created by admin on Wed Apr 02 16:29:47 GMT 2025 , Edited by admin on Wed Apr 02 16:29:47 GMT 2025
PRIMARY
INN
12308
Created by admin on Wed Apr 02 16:29:47 GMT 2025 , Edited by admin on Wed Apr 02 16:29:47 GMT 2025
PRIMARY
Related Record Type Details
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
INSERTED GENE EXPRESSION VECTOR Enekinragene inzadenovec transgene insert 4M4V4M9VWF