IOFLUPANE I-123

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C18H23FINO2
Molecular Weight	427.2847
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of IOFLUPANE I-123

Structure Search

SMILES

COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1C3=CC=C([123I])C=C3)N2CCCF

InChI

InChIKey=HXWLAJVUJSVENX-HFIFKADTSA-N

InChI=1S/C18H23FINO2/c1-23-18(22)17-15(12-3-5-13(20)6-4-12)11-14-7-8-16(17)21(14)10-2-9-19/h3-6,14-17H,2,7-11H2,1H3/t14-,15+,16+,17-/m0/s1/i20-4

HIDE SMILES / InChI

Molecular Formula	C18H23FINO2
Molecular Weight	427.2847
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:37:28 UTC 2023` Edited by `admin` on `Fri Dec 15 15:37:28 UTC 2023`
Record UNII	3MM99T8R5Q
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IOFLUPANE I-123

Common Name

English

IOFLUPANE I 123 [USAN]

Common Name

English

IOFLUPANE I 123 [MI]

Common Name

English

V09AB03

Code

English

IOFLUPANE I-123 [ORANGE BOOK]

Common Name

English

IOFLUPANE (123I)

Official Name

English

IOFLUPANE (123L)

Common Name

English

(123I)FP-CIT

Common Name

English

V-09AB03

Code

English

IOFLUPANE (SUP 123)I

Common Name

English

ioflupane (¹²³I) [INN]

Common Name

English

IOFLUPANE (123L) [EMA EPAR]

Common Name

English

DATSCAN

Brand Name

English

8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLIC ACID, 8-(3-FLUOROPROPYL)-3-(4-(IODO-(SUP 123)I)PHENYL)-, METHYL ESTER, (1R,2S,3S,5S)-

Common Name

English

METHYL 8-(3-FLUOROPROPYL)-3.BETA.-(P-IODO-(SUP 123)I-PHENYL)-1.ALPHA.H,5.ALPHA.H-NORTROPANE-2.BETA.-CARBOXYLATE

Common Name

English

IOFLUPANE I-123 [VANDF]

Common Name

English

IOFLUPANE I 123

Official Name

English

IOFLUPANE (SUP 123)I [EMA EPAR]

Common Name

English

FP-CIT I-123

Common Name

English

IOFLUPANE, I-123

Common Name

English

Ioflupane (123I) [WHO-DD]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000177914

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

NCI_THESAURUS

C1446

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

EMA ASSESSMENT REPORTS

DATSCAN (AUTHORIZED: PARKINSON DISEASE)

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

EMA ASSESSMENT REPORTS

DATSCAN (AUTHORIZED: ALZHEIMER DISEASE)

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

EMA ASSESSMENT REPORTS

DATSCAN (AUTHORIZED: LEWY BODY DISEASE)

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

WHO-VATC

QV09AB03

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

EMA ASSESSMENT REPORTS

DATSCAN (AUTHORIZED: TOMOGRAPHY, EMISSION-COMPUTED, SINGLE PHOTON)

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

WHO-ATC

V09AB03

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

Code System Code Type Description

WIKIPEDIA

IOFLUPANE (123I)

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

CHEBI

68855

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

CAS

155798-07-5

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

INN

7500

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

USAN

WW-152

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

SMS_ID

100000089027

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

LACTMED

Ioflupane I 123

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

EPA CompTox

DTXSID90935291

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

ChEMBL

CHEMBL2110569

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

DRUG BANK

DB08824

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

FDA UNII

3MM99T8R5Q

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

NCI_THESAURUS

C80644

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

EVMPD

SUB08221MIG

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

PUBCHEM

3086674

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

MERCK INDEX

m6363

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

Merck Index

DAILYMED

3MM99T8R5Q

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

DRUG CENTRAL

4230

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

RXCUI

1426874

Created by admin on Fri Dec 15 15:37:29 UTC 2023 , Edited by admin on Fri Dec 15 15:37:29 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					F202H3PMO2

SODIUM-DEPENDENT DOPAMINE TRANSPORTER

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					3MM99T8R5Q

IOFLUPANE I-123

EXCRETED UNCHANGED

Qualification:

FECAL

Amount:


					3MM99T8R5Q

IOFLUPANE I-123

EXCRETED UNCHANGED

Qualification:

URINE

Amount:


					3MM99T8R5Q

IOFLUPANE I-123

EXCRETED UNCHANGED

Comments:

Elimination from the whole body via voided urine was approximately 60% of %IA at 48 hours post injection.

Qualification:

URINE

Amount:

Related Record Type Details


					S0MHU698ZB

METHYL 3-(4-(IODO-123I)PHENYL)-8-AZABICYCLO(3.2.1)OCTANE-2-CARBOXYLATE, (1R,2S,3S,5S)-

METABOLITE -> PARENT

Amount:


					5FUN7WNM9M

(1S,3S,4S,5R)-8-(3-FLUOROPROPYL)-3-(4-IODANYLPHENYL)-8-AZABICYCLO(3.2.1)OCTANE-4-CARBOXYLIC ACID

METABOLITE -> PARENT


					NRN2X6YX89

(1S,3S,4S,5R)-3-(4-IODANYLPHENYL)-8-AZABICYCLO(3.2.1)OCTANE-4-CARBOXYLIC ACID

METABOLITE -> PARENT

Related Record Type Details


					3MM99T8R5Q

IOFLUPANE I-123

ACTIVE MOIETY