Surovatamig

Investigational

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 06:51:11 GMT 2025` Edited by `admin` on `Wed Apr 02 06:51:11 GMT 2025`
Protein Type	BISPECIFIC ANTIBODY
Protein Sub Type	IGG4\|KAPPA
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	3QW12I37H1
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Surovatamig

Official Name

English

AZD-0486

Preferred Name

English

AZD0486

Code

English

surovatamig [INN]

Common Name

English

immunoglobulin (H-gamma4_L-kappa)_VH-G4(h-CH2-CH3), anti-[Homo sapiens CD3D (CD3 delta) and CD3E (CD3 epsilon, Leu-4) dimer] and anti-[Homo sapiens CD19 (B lymphocyte surface antigen B4, Leu-12)], Homo sapiens and humanized monoclonal antibody asymetric,

Common Name

English

H-gamma4 heavy chain anti-CD3D/CD3E dimer, Homo sapiens (1-450) [VH (Homo sapiens IGHV3-9*01 (100%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.16] (26-33.51-58.97-112)) (1-123)-Homo sapiens IGHG4*01 nG4m(a) CH2 L92, G4v5 h P10, G4v4 CH2 A1.3, A1.2, G4v32 CH

Common Name

English

TNB-486

Code

English

Immunoglobulin G4 [231-proline,237-alanine,238-alanine,369-tryptophan], bispecific, anti-(human CD3 antigen) (human monoclonal AZD0486 ?4-chain) disulfide with human monoclonal AZD0486 ?-chain, (229?124?),(232?127?)-bis(disulfide) with immunoglobulin [12

Common Name

English

Code System Code Type Description

NCI_THESAURUS

C178577