U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

2018
425
Substance Class Nucleic Acid
Created
by admin
on Mon Mar 31 22:41:54 GMT 2025
Edited
by admin
on Mon Mar 31 22:41:54 GMT 2025
Nucleic Acid Type RNAI
Sequence Type COMPLETE
Record UNII
50FKX8CB2Y
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ALN-TTR02
Preferred Name English
PATISIRAN
INN  
INN   USAN  
Official Name English
RNA, (A-U-G-G-A-A-UM-A-C-U-C-U-U-G-G-U-UM-A-C-DT-DT), COMPLEX WITH RNA (G-UM-A-A-CM-CM-A-A-G-A-G-UM-A-UM-UM-CM-CM-A-UM-DT-DT) (1:1)
Common Name English
SAR-438037
Code English
PATISIRAN [MI]
Common Name English
GENZ-438027
Common Name English
Patisiran [WHO-DD]
Common Name English
ALN-18328
Code English
PATISIRAN [USAN]
Common Name English
patisiran [INN]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C129821
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
FDA ORPHAN DRUG 371112
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
WHO-ATC N07XX12
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
Code System Code Type Description
SMS_ID
100000175476
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
EPA CompTox
DTXSID301027892
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
DAILYMED
50FKX8CB2Y
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
RXCUI
2053490
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
WIKIPEDIA
Patisiran
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
DRUG BANK
DB14582
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
USAN
DE-158
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
DRUG CENTRAL
5313
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
CAS
1420706-45-1
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
NCI_THESAURUS
C116792
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
FDA UNII
50FKX8CB2Y
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
MERCK INDEX
m12092
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
INN
9793
Created by admin on Mon Mar 31 22:41:55 GMT 2025 , Edited by admin on Mon Mar 31 22:41:55 GMT 2025
PRIMARY
Sugar Site Range Site Count
D-Ribose (RNA) 1_1;1_3-1_4;1_7-1_11;1_13;1_18;2_1-2_6;2_8-2_16;2_18-2_19 27 / 42
2'-O-Methyl-Ribose 1_2;1_5-1_6;1_12;1_14-1_17;1_19;2_7;2_17 11 / 42
Deoxyribose (DNA) 1_20-1_21;2_20-2_21 4 / 42
Linkage Site Range Site Count
Phosphate 1_2-1_21;2_2-2_21 40 / 40
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TRANSTHYRETIN V30M
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Mutation associated with ATTR amyloidosis
Related Record Type Details
PATISIRAN
ACTIVE MOIETY
NIH
NCATS
PRIVACY NOTICE
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
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