DOMPERIDONE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C22H24ClN5O2
Molecular Weight	425.911
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DOMPERIDONE

Structure Search

SMILES

ClC1=CC=C2N(C3CCN(CCCN4C(=O)NC5=C4C=CC=C5)CC3)C(=O)NC2=C1

InChI

InChIKey=FGXWKSZFVQUSTL-UHFFFAOYSA-N

InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30)

HIDE SMILES / InChI

Molecular Formula	C22H24ClN5O2
Molecular Weight	425.911
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:16:53 UTC 2023` Edited by `admin` on `Fri Dec 15 15:16:53 UTC 2023`
Record UNII	5587267Z69
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

DOMPERIDONE

Official Name

English

DOMPERIDONE [MART.]

Common Name

English

Domperidone [WHO-DD]

Common Name

English

DOMPERIDONE [JAN]

Common Name

English

NSC-299589

Code

English

5-Chloro-1-[1-[3-(2-oxo-1-benzimidazolinyl)propyl]-4-piperidyl]-2-benzimidazolinone

Systematic Name

English

2H-BENZIMIDAZOL-2-ONE, 5-CHLORO-1-(1-(3-(2,3-DIHYDRO-2-OXO-1H-BENZIMIDAZOL-1-YL)PROPYL)-4-PIPERIDINYL)-1,3-DIHYDRO-

Systematic Name

English

R-33812

Code

English

MOTILIUM

Brand Name

English

domperidone [INN]

Common Name

English

NSC-759575

Code

English

DOMPERIDONE [USAN]

Common Name

English

R 33,812

Code

English

DOMPERIDONE [GREEN BOOK]

Common Name

English

DOMPERIDONE [EP MONOGRAPH]

Common Name

English

DOMPERIDONE [VANDF]

Common Name

English

DOMPERIDONE [MI]

Common Name

English

Classification Tree Code System Code

CFR

21 CFR 520.766

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

LIVERTOX

NBK548487

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

WHO-VATC

QA03FA03

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

WHO-VATC

QP51AX24

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

NCI_THESAURUS

C29710

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

FDA ORPHAN DRUG

336111

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

WHO-ATC

A03FA03

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

Code System Code Type Description

WIKIPEDIA

DOMPERIDONE

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

MERCK INDEX

m4737

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

Merck Index

DRUG BANK

DB01184

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

LACTMED

Domperidone

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

ECHA (EC/EINECS)

260-968-7

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

FDA UNII

5587267Z69

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

ChEMBL

CHEMBL219916

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

MESH

D004294

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

DAILYMED

5587267Z69

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

DRUG CENTRAL

945

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

NSC

759575

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

NSC

299589

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

EVMPD

SUB06361MIG

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

EPA CompTox

DTXSID1045116

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

PUBCHEM

3151

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

RXCUI

3626

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

RxNorm

IUPHAR

965

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

NCI_THESAURUS

C454

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

SMS_ID

100000092257

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

CHEBI

31515

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

CAS

57808-66-9

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

INN

4110

Created by admin on Fri Dec 15 15:16:53 UTC 2023 , Edited by admin on Fri Dec 15 15:16:53 UTC 2023

PRIMARY

Related Record Type Details


					899U5WF46A

DOMPERIDONE MALEATE

SALT/SOLVATE -> PARENT

Amount:


					22ES734693

MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> SUBSTRATE


					LR0F81F33L

ALDEHYDE OXIDASE

METABOLIC ENZYME -> INHIBITOR

Qualification:

IC50

Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Amount:


					SEV29N8JND

POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2

OFF-TARGET->INHIBITOR

Qualification:

IC50

Amount:


					C55S87J9RC

DOMPERIDONE ACETATE

SALT/SOLVATE -> PARENT

Amount:

Related Record Type Details


					ZE6EAB6RGV

5-Hydroxydomperidone

METABOLITE -> PARENT

Amount:


					53TAT94YDS

5-CHLORO-1-(4-PIPERIDINYL)-2-BENZIMIDAZOLINONE

METABOLITE -> PARENT

Amount:

Related Record Type Details


					53TAT94YDS

5-CHLORO-1-(4-PIPERIDINYL)-2-BENZIMIDAZOLINONE

IMPURITY -> PARENT

Amount:


					YFF7LGR2XQ

4-(5-CHLORO-2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL)-1-FORMYLPIPERIDINE

IMPURITY -> PARENT

Amount:


					JJ3HBB9FWS

1,3-BIS(3-(4-(5-CHLORO-2-OXO-3H-BENZIMIDAZOL-1-YL)PIPERIDIN-1-YL)PROPYL)BENZIMIDAZOL-2-ONE

IMPURITY -> PARENT

Amount:


					SU3NPR78Z6

1-(3-(4-(5-CHLORO-2-OXO-3H-BENZIMIDAZOL-1-YL)PIPERIDIN-1-YL)PROPYL)-3-(3-(2-OXO-3H-BENZIMIDAZOL-1-YL)PROPYL)BENZIMIDAZOL-2-ONE

IMPURITY -> PARENT

Amount:


					FC9E589L8T

5-CHLORO-3-(3-(2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL)PROPYL)-1-(1-(3-(2-OXO-2,3-DIHYDRO-1H-BENZIMIDAZOL-1-YL) PROPYL) PIPERIDIN-4-YL)- 1,3-DIHYDRO-2H-BENZIMIDAZOL-2-ONE

IMPURITY -> PARENT

Amount:

Related Record Type Details


					5587267Z69

ACTIVE MOIETY

Amount: