IOLOPRIDE I-123

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C15H21IN2O3
Molecular Weight	400.2444
Optical Activity	UNSPECIFIED
Defined Stereocenters	1 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CCN1CCC[C@H]1CNC(=O)C2=C(OC)C=CC([123I])=C2O

InChI

InChIKey=CANPFCFJURGKAX-SCBSARHOSA-N

InChI=1S/C15H21IN2O3/c1-3-18-8-4-5-10(18)9-17-15(20)13-12(21-2)7-6-11(16)14(13)19/h6-7,10,19H,3-5,8-9H2,1-2H3,(H,17,20)/t10-/m0/s1/i16-4

HIDE SMILES / InChI

Molecular Formula	C15H21IN2O3
Molecular Weight	400.2444
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	1 / 1
E/Z Centers	0
Optical Activity	UNSPECIFIED

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/11139051 | https://www.ncbi.nlm.nih.gov/pubmed/20305408

IOLOPRIDE I-123 (also known as I-123 iodobenzamide), a radioactive drug that can be seen by Single-photon emission computed tomography. This drug binds to the some dopamine receptors and can be used in the neonatal period. It shows the biochemical maturation of D2 receptors and also manifests the deleterious effect of perinatal hypoxic-ischemic events on D2 receptors.

Approval Year

PubMed

Title	Date	PubMed
D2 receptor imaging in neonates using I-123 iodobenzamide brain SPECT.	2001-01	11139051
Iodine-123-iodobenzamide binding in parkinsonism: reduction by dopamine agonists but not L-Dopa.	1996-07	8965179
Imaging of D2 dopamine receptors of patients with Parkinson's disease using single photon emission computed tomography and iodobenzamide I 123.	1993-05	8489408

Substance Class	Chemical Created by `admin` on `Mon Mar 31 18:46:24 GMT 2025` Edited by `admin` on `Mon Mar 31 18:46:24 GMT 2025`
Record UNII	5E76SOQ99K
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

IOLOPRIDE (123I)

Preferred Name

English

IOLOPRIDE I-123

Common Name

English

BENZAMIDE, N-(((2S)-1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-(IODO-123I)-6-METHOXY-

Systematic Name

English

IOLOPRIDE I 123

Common Name

English

S-(-)-N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-(123I)IODO-6-METHOXYBENZAMIDE

Common Name

English

IBZM I-123

Common Name

English

(I123)IBZM

Common Name

English

123I-IBZM

Common Name

English

BENZAMIDE, N-((1-ETHYL-2-PYRROLIDINYL)METHYL)-2-HYDROXY-3-(IODO-123I)-6-METHOXY-, (S)-

Common Name

English

Iolopride (123 i) [WHO-DD]

Common Name

English

iolopride (¹²³I) [INN]

Common Name

English

IOLOPRIDE ((SUP 123)I)

Common Name

English

IOLOPRIDE (123 I)

Common Name

English

N-(((2S)-1-ETHYL-2-PYRROLIDINYL)METHYL)-6-HYDROXY-5-(((SUP 123)I)IODO)-O-ANISAMIDE

Common Name

English

IODOBENZAMIDE I-123

Common Name

English

IOLOPRIDE, I-123

Common Name

English

Classification Tree Code System Code

WHO-ATC

V09AB02