Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C8H16N2O3.2ClH |
| Molecular Weight | 261.146 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
Cl.Cl.CC(=O)NCCCC[C@H](N)C(O)=O
InChI
InChIKey=DJZSLFLQVHLNPD-KLXURFKVSA-N
InChI=1S/C8H16N2O3.2ClH/c1-6(11)10-5-3-2-4-7(9)8(12)13;;/h7H,2-5,9H2,1H3,(H,10,11)(H,12,13);2*1H/t7-;;/m0../s1
| Molecular Formula | C8H16N2O3 |
| Molecular Weight | 188.2242 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 1 / 1 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
| Molecular Formula | ClH |
| Molecular Weight | 36.461 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Nε-lysine acetylation of a bacterial transcription factor inhibits Its DNA-binding activity. | 2010-12-31 |
|
| Transition state of ADP-ribosylation of acetyllysine catalyzed by Archaeoglobus fulgidus Sir2 determined by kinetic isotope effects and computational approaches. | 2010-09-08 |
|
| N(epsilon)-Modified lysine containing inhibitors for SIRT1 and SIRT2. | 2010-08-01 |
|
| Synthetic biology approaches in drug discovery and pharmaceutical biotechnology. | 2010-06 |
|
| Degradation of 1-deoxy-D-erythro-hexo-2,3-diulose in the presence of lysine leads to formation of carboxylic acid amides. | 2010-05-26 |
|
| A convenient method for genetic incorporation of multiple noncanonical amino acids into one protein in Escherichia coli. | 2010-04 |
|
| Substrate specificity of SIRT1-catalyzed lysine Nepsilon-deacetylation reaction probed with the side chain modified Nepsilon-acetyl-lysine analogs. | 2010-02 |
|
| A method for genetically installing site-specific acetylation in recombinant histones defines the effects of H3 K56 acetylation. | 2009-10-09 |
|
| Plasmodium falciparum Sir2 is an NAD+-dependent deacetylase and an acetyllysine-dependent and acetyllysine-independent NAD+ glycohydrolase. | 2008-09-23 |
|
| Adding l-lysine derivatives to the genetic code of mammalian cells with engineered pyrrolysyl-tRNA synthetases. | 2008-07-11 |
|
| Utility of immonium ions for assignment of epsilon-N-acetyllysine-containing peptides by tandem mass spectrometry. | 2008-05-01 |
|
| Genetically encoding N(epsilon)-acetyllysine in recombinant proteins. | 2008-04 |
|
| A spectrophotometric assay for histone deacetylase 8. | 2008-01-01 |
|
| Substituting N(epsilon)-thioacetyl-lysine for N(epsilon)-acetyl-lysine in peptide substrates as a general approach to inhibiting human NAD(+)-dependent protein deacetylases. | 2008-01 |
|
| Characterization of Nalpha-benzyloxycarbonyl-L-lysine oxidizing enzyme from Rhodococcus sp. AIU Z-35-1. | 2007-09 |
|
| N(epsilon)-methanesulfonyl-lysine as a non-hydrolyzable functional surrogate for N(epsilon)-acetyl-lysine. | 2007-03-21 |
|
| Nepsilon-thioacetyl-lysine: a multi-facet functional probe for enzymatic protein lysine Nepsilon-deacetylation. | 2006-07-15 |
|
| Proteomic analysis of organ-specific post-translational lysine-acetylation and -methylation in mice by use of anti-acetyllysine and -methyllysine mouse monoclonal antibodies. | 2005-12 |
|
| Purification and characterization of a novel aminoacylase from Streptomyces mobaraensis. | 2005-10 |
|
| Kinetics and comparative reactivity of human class I and class IIb histone deacetylases. | 2004-08-31 |
|
| Four different clones of mouse anti-acetyllysine monoclonal antibodies having different recognition properties share a common immunoglobulin framework structure. | 2003-01-15 |
|
| Switching osmolyte strategies: response of Methanococcus thermolithotrophicus to changes in external NaCl. | 2001-11-15 |
|
| A case of hyperlysinemia: biochemical and clinical observations. | 1967-04 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 15:08:32 GMT 2025
by
admin
on
Wed Apr 02 15:08:32 GMT 2025
|
| Record UNII |
5F28VMW9DT
|
| Record Status |
Validated (UNII)
|
| Record Version |
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Created by
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5F28VMW9DT
Created by
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2408937-00-6
Created by
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