VILOXAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C13H19NO3
Molecular Weight	237.2949
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of VILOXAZINE

Structure Search

SMILES

CCOC1=C(OCC2CNCCO2)C=CC=C1

InChI

InChIKey=YWPHCCPCQOJSGZ-UHFFFAOYSA-N

InChI=1S/C13H19NO3/c1-2-15-12-5-3-4-6-13(12)17-10-11-9-14-7-8-16-11/h3-6,11,14H,2,7-10H2,1H3

HIDE SMILES / InChI

Molecular Formula	C13H19NO3
Molecular Weight	237.2949
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:44:44 UTC 2023` Edited by `admin` on `Fri Dec 15 16:44:44 UTC 2023`
Record UNII	5I5Y2789ZF
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

VILOXAZINE

Official Name

English

viloxazine [INN]

Common Name

English

Viloxazine [WHO-DD]

Common Name

English

VILOXAZINE [MI]

Common Name

English

MORPHOLINE, 2-((2-ETHOXYPHENOXY)METHYL)-

Systematic Name

English

(±)-2-(O-ETHOXYPHENOXYMETHYL)MORPHOLINE

Common Name

English

VILOXAZIN

Common Name

English

VILOXAZINE [VANDF]

Common Name

English

Classification Tree Code System Code

WHO-ATC

N06AX09

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

WHO-VATC

QN06AX09

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

WIKIPEDIA

Designer-drugs-Viloxazine

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

NCI_THESAURUS

C265

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

Code System Code Type Description

DAILYMED

5I5Y2789ZF

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

FDA UNII

5I5Y2789ZF

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

MERCK INDEX

m11448

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

Merck Index

INN

3489

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

DRUG BANK

DB09185

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

ChEMBL

CHEMBL306700

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

WIKIPEDIA

VILOXAZINE

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

ECHA (EC/EINECS)

256-281-7

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

EPA CompTox

DTXSID6057900

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

MESH

D014745

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

CAS

46817-91-8

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

RXCUI

11196

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

RxNorm

DRUG CENTRAL

2820

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

PUBCHEM

5666

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

SMS_ID

100000079104

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

EVMPD

SUB00049MIG

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

NCI_THESAURUS

C152877

Created by admin on Fri Dec 15 16:44:44 UTC 2023 , Edited by admin on Fri Dec 15 16:44:44 UTC 2023

PRIMARY

Related Record Type Details


					3318TFY23Q

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A9

METABOLIC ENZYME -> SUBSTRATE

Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

REVERSIBLE

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

REVERSIBLE

Amount:


					OQW30I1332

VILOXAZINE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					VK4SQL11C0

CYTOCHROME P450 1A2

METABOLIC ENZYME -> INDUCER

Amount:


					HP6E97INCN

VILOXAZINE, (R)-

ENANTIOMER -> RACEMATE

Amount:


					0UY97CSG1T

CYTOCHROME P450 2B6

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

REVERSIBLE

Amount:


					37Z27K60U2

VILOXAZINE, (S)-

ENANTIOMER -> RACEMATE

Amount:


					0UY97CSG1T

CYTOCHROME P450 2B6

METABOLIC ENZYME -> INDUCER

Amount:


					VK4SQL11C0

CYTOCHROME P450 1A2

METABOLIC ENZYME -> INHIBITOR

Interaction Type:

REVERSIBLE

Amount:


					2Z5HW3OR67

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 2B15

METABOLIC ENZYME -> SUBSTRATE

Amount:


					5I5Y2789ZF

EXCRETED UNCHANGED

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Comments:

Viloxazine is 76-82% bound to human plasma proteins over the blood concentration range of 0.5 mcg/mL to 10 mcg/mL.

Interaction Type:

BINDING

Amount:


					8E4LAA4357

CYTOCHROME P450 2D6

METABOLIC ENZYME -> SUBSTRATE

Amount:

Related Record Type Details


					3KT6SV7DTM

5-HYDROXYVILOXAZINE

METABOLITE -> PARENT

Comments:

Converted to glucuronide

Interaction Type:

MAJOR

Amount:


					PD62UVK8MD

5-HYDROXYVILOXAZINE GLUCURONIDE

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR

Qualification:

URINE

Amount:

Related Record Type Details


					5I5Y2789ZF

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Tmax	PHARMACOKINETIC