MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 19:57:00 GMT 2025` Edited by `admin` on `Tue Apr 01 19:57:00 GMT 2025`
Protein Type	ENZYME
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	5K47RF8GE8
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 11

Common Name

English

MIXED LINEAGE KINASE 3

Preferred Name

English

SRC-HOMOLOGY 3 DOMAIN-CONTAINING PROLINE-RICH KINASE

Common Name

English

MLK3

Common Name

English

SPRK

Common Name

English

PTK1

Common Name

English

Code System Code Type Description

WIKIPEDIA

MAP3K11

Created by admin on Tue Apr 01 19:57:00 GMT 2025 , Edited by admin on Tue Apr 01 19:57:00 GMT 2025

PRIMARY

EC (ENZYME CLASS)

EC 2.7.11.25

Created by admin on Tue Apr 01 19:57:00 GMT 2025 , Edited by admin on Tue Apr 01 19:57:00 GMT 2025

PRIMARY

FDA UNII

5K47RF8GE8

Created by admin on Tue Apr 01 19:57:00 GMT 2025 , Edited by admin on Tue Apr 01 19:57:00 GMT 2025

PRIMARY

UNIPROT

Q16584

Created by admin on Tue Apr 01 19:57:00 GMT 2025 , Edited by admin on Tue Apr 01 19:57:00 GMT 2025

PRIMARY

CAS

864881-68-5

Created by admin on Tue Apr 01 19:57:00 GMT 2025 , Edited by admin on Tue Apr 01 19:57:00 GMT 2025

PRIMARY

PHAROS

Q16584

Created by admin on Tue Apr 01 19:57:00 GMT 2025 , Edited by admin on Tue Apr 01 19:57:00 GMT 2025

PRIMARY

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Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_281] [1_555] [1_556] [2_281] [2_555] [2_556]		SERINE		DEXFOSFOSERINE	VI4F0K069V
AMINO ACID SUBSTITUTION	[1_277] [2_277]		THREONINE		THREONINE PHOSPHATE	3L4WX7B1EI

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED)	CHEMICAL