U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 20:19:24 GMT 2025
Edited
by admin
on Tue Apr 01 20:19:24 GMT 2025
Protein Type MONOCLONAL ANTIBODY
Protein Sub Type IGG1
Sequence Origin MOUSE CHIMERIC
Sequence Type COMPLETE
Record UNII
5P637IXG16
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TOMUZOTUXIMAB
INN  
INN  
Official Name English
IMMUNOGLOBULIN G1, ANTI-(HUMAN EPIDERMAL GROWTH FACTOR RECEPTOR) (HUMAN-MUS MUSCULUS MONOCLONAL C225 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL C225 .KAPPA.-CHAIN, DIMER, GLYCOFORM
Preferred Name English
Tomuzotuximab [WHO-DD]
Common Name English
tomuzotuximab [INN]
Common Name English
Code System Code Type Description
FDA UNII
5P637IXG16
Created by admin on Tue Apr 01 20:19:24 GMT 2025 , Edited by admin on Tue Apr 01 20:19:24 GMT 2025
PRIMARY
CAS
1646321-00-7
Created by admin on Tue Apr 01 20:19:24 GMT 2025 , Edited by admin on Tue Apr 01 20:19:24 GMT 2025
PRIMARY
SMS_ID
300000021832
Created by admin on Tue Apr 01 20:19:24 GMT 2025 , Edited by admin on Tue Apr 01 20:19:24 GMT 2025
PRIMARY
NCI_THESAURUS
C152692
Created by admin on Tue Apr 01 20:19:24 GMT 2025 , Edited by admin on Tue Apr 01 20:19:24 GMT 2025
PRIMARY
DRUG BANK
DB15178
Created by admin on Tue Apr 01 20:19:24 GMT 2025 , Edited by admin on Tue Apr 01 20:19:24 GMT 2025
PRIMARY
INN
10334
Created by admin on Tue Apr 01 20:19:24 GMT 2025 , Edited by admin on Tue Apr 01 20:19:24 GMT 2025
PRIMARY
From To
1_22 1_95
1_146 1_202
1_263 1_323
1_369 1_427
2_22 2_95
2_146 2_202
2_263 2_323
2_369 2_427
3_23 3_88
3_134 3_194
4_23 4_88
4_134 4_194
1_222 3_214
1_228 2_228
1_231 2_231
Glycosylation Type MAMMALIAN
Glycosylation Link Type Site
N 3_41
N 4_41
Related Record Type Details
EPIDERMAL GROWTH FACTOR RECEPTOR
TARGET -> INHIBITOR
Related Record Type Details
TOMUZOTUXIMAB
ACTIVE MOIETY

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID REMOVAL [1_449] [2_449] C-TERMINUS K LYSINE K3Z4F929H6
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT(CALCULATED) CHEMICAL
Molecular Formula CHEMICAL
NIH
NCATS
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