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Details

Stereochemistry ACHIRAL
Molecular Formula C21H16ClF3N4O3.C7H8O3S
Molecular Weight 637.027
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of SORAFENIB TOSYLATE

SMILES

CC1=CC=C(C=C1)S(O)(=O)=O.CNC(=O)C2=CC(OC3=CC=C(NC(=O)NC4=CC(=C(Cl)C=C4)C(F)(F)F)C=C3)=CC=N2

InChI

InChIKey=IVDHYUQIDRJSTI-UHFFFAOYSA-N
InChI=1S/C21H16ClF3N4O3.C7H8O3S/c1-26-19(30)18-11-15(8-9-27-18)32-14-5-2-12(3-6-14)28-20(31)29-13-4-7-17(22)16(10-13)21(23,24)25;1-6-2-4-7(5-3-6)11(8,9)10/h2-11H,1H3,(H,26,30)(H2,28,29,31);2-5H,1H3,(H,8,9,10)

HIDE SMILES / InChI
Molecular Formula C21H16ClF3N4O3
Molecular Weight 464.825
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE
Molecular Formula C7H8O3S
Molecular Weight 172.202
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:49:15 UTC 2023
Edited
by admin
on Fri Dec 15 15:49:15 UTC 2023
Record UNII
5T62Q3B36J
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
SORAFENIB TOSYLATE
MI   ORANGE BOOK   USAN  
USAN  
Official Name English
SORAFENIB TOSYLATE [ORANGE BOOK]
Common Name English
4-(4-(((4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)CARBAMOYL)AMINO)PHENOXY)-N-METHYLPYRIDINE-2-CARBOXAMIDE 4-METHYLBENZENESULPHONATE
Systematic Name English
SORAFENIB TOSILATE
JAN   MART.   WHO-DD  
Common Name English
4-(4-(((4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)CARBAMOYL)AMINO)PHENOXY)-N-METHYLPYRIDINE-2-CARBOXAMIDE 4-METHYLBENZENESULFONATE
Systematic Name English
SORAFENIB TOSYLATE [USP-RS]
Common Name English
4-(4-(3-(4-CHLORO-3-(TRIFLUOROMETHYL)PHENYL)UREIDO)PHENOXY)-N2-METHYLPYRIDINE-2-CARBOXAMIDE MONO (4-METHYLBENZENESULFONATE)
Systematic Name English
SORAFENIB TOSYLATE [USAN]
Common Name English
SORAFENIB TOSYLATE [MI]
Common Name English
SORAFENIB TOSILATE [JAN]
Common Name English
SORAFENIB TOSYLATE [USP MONOGRAPH]
Common Name English
NEXAVAR
Brand Name English
BAY 54-9085
Code English
1-[4-Chloro-3-(trifluoromethyl)phenyl]-3-[4-[[2-(methylcarbamoyl)pyridin-4-yl]oxy]phenyl]urea mono(4-methylbenzenesulfonate)
Systematic Name English
SORAFENIB TOSILATE [EP MONOGRAPH]
Common Name English
Sorafenib tosilate [WHO-DD]
Common Name English
SORAFENIB TOSILATE [MART.]
Common Name English
BAY-54-9085
Code English
Classification Tree Code System Code
EU-Orphan Drug EU/3/06/364
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
NCI_THESAURUS C1742
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
EMA ASSESSMENT REPORTS NEXAVAR (AUTHORIZED: CARCINOMA, HEPATOCELLULAR)
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
NCI_THESAURUS C1404
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
NCI_THESAURUS C129825
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
EMA ASSESSMENT REPORTS NEXAVAR (AUTHORIZED: CARCINOMA, RENAL CELL)
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
Code System Code Type Description
EPA CompTox
DTXSID9047839
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
RXCUI
597744
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY RxNorm
NCI_THESAURUS
C2194
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
MERCK INDEX
m10116
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY Merck Index
CHEBI
50928
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
ChEMBL
CHEMBL1336
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
DRUG BANK
DBSALT000165
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
FDA UNII
5T62Q3B36J
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
RS_ITEM_NUM
1615876
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
SMS_ID
100000090319
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
DAILYMED
5T62Q3B36J
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
CAS
475207-59-1
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
USAN
UU-03
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
PUBCHEM
406563
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
EVMPD
SUB22347
Created by admin on Fri Dec 15 15:49:15 UTC 2023 , Edited by admin on Fri Dec 15 15:49:15 UTC 2023
PRIMARY
Related Record Type Details
Structure of SORAFENIB
PARENT -> SALT/SOLVATE
Related Record Type Details
Structure of SORAFENIB
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