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Details

Stereochemistry ABSOLUTE
Molecular Formula C11H15N5O5
Molecular Weight 297.2673
Optical Activity UNSPECIFIED
Defined Stereocenters 4 / 4
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of NELARABINE

SMILES

COC1=NC(N)=NC2=C1N=CN2[C@@H]3O[C@H](CO)[C@@H](O)[C@@H]3O

InChI

InChIKey=IXOXBSCIXZEQEQ-UHTZMRCNSA-N
InChI=1S/C11H15N5O5/c1-20-9-5-8(14-11(12)15-9)16(3-13-5)10-7(19)6(18)4(2-17)21-10/h3-4,6-7,10,17-19H,2H2,1H3,(H2,12,14,15)/t4-,6-,7+,10-/m1/s1

HIDE SMILES / InChI
Molecular Formula C11H15N5O5
Molecular Weight 297.2673
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 4 / 4
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Fri Dec 15 15:56:14 UTC 2023
Edited
by admin
on Fri Dec 15 15:56:14 UTC 2023
Record UNII
60158CV180
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
NELARABINE
EMA EPAR   INN   JAN   MART.   MI   ORANGE BOOK   USAN   VANDF   WHO-DD  
INN   USAN  
Official Name English
506U78
Code English
ARRANON
Brand Name English
NELARABINE [ORANGE BOOK]
Common Name English
NELARABINE [EMA EPAR]
Common Name English
506U
Code English
ATTRIANCE
Brand Name English
nelarabine [INN]
Common Name English
NELZARABINE
Common Name English
NELARABINE [MART.]
Common Name English
MAY
Code English
9H-PURIN-2-AMINE, 9-.BETA.-D-ARABINOFURANOSYL-6-METHOXY-
Systematic Name English
NELARABINE [MI]
Common Name English
NELARABINE [VANDF]
Common Name English
9-.BETA.-D-ARABINOFURANOSYL-6-METHOXY-9H-PURIN-2-AMINE
Common Name English
NSC-755985
Code English
Nelarabine [WHO-DD]
Common Name English
NSC-686673
Code English
NSC-759876
Code English
NELARABINE [JAN]
Common Name English
NELARABINE [USAN]
Common Name English
GW-506U78
Code English
2-AMINO-9-.BETA.-D-ARABINOFURANOSYL-6-METHOXY-9H-PURINE
Systematic Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 125999
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
WHO-ATC L01BB07
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
EU-Orphan Drug EU/3/05/293
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
NDF-RT N0000175595
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
NCI_THESAURUS C1556
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
EMA ASSESSMENT REPORTS ATTRIANCE (AUTHORIZED: PRECURSOR T-CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA)
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
LIVERTOX NBK548515
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
WHO-VATC QL01BB07
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
NDF-RT N0000000233
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
FDA ORPHAN DRUG 184404
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
Code System Code Type Description
MESH
C104457
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
SMS_ID
100000085469
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
WIKIPEDIA
NELARABINE
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
PUBCHEM
3011155
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
DRUG BANK
DB01280
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
DAILYMED
60158CV180
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
MERCK INDEX
m7797
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY Merck Index
INN
7704
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
FDA UNII
60158CV180
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
CHEBI
63612
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
EVMPD
SUB09188MIG
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
RXCUI
274771
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID6046842
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
IUPHAR
7090
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
NSC
686673
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
CAS
121032-29-9
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
NSC
755985
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
ChEMBL
CHEMBL1201112
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
DRUG CENTRAL
1892
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
NCI_THESAURUS
C1704
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
NSC
759876
Created by admin on Fri Dec 15 15:56:14 UTC 2023 , Edited by admin on Fri Dec 15 15:56:14 UTC 2023
PRIMARY
Related Record Type Details
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
Plasma protein binding is independent on nelarabine concentrations.
BINDING
Structure of NELARABINE
EXCRETED UNCHANGED
URINE
Related Record Type Details
Structure of Allantoin
METABOLITE -> PARENT
Structure of XANTHINE
METABOLITE -> PARENT
MINOR
Structure of GUANINE
METABOLITE -> PARENT
Structure of 6-METHOXYGUANINE
METABOLITE -> PARENT
Structure of URIC ACID
METABOLITE -> PARENT
Structure of ARAGUANOSINE
METABOLITE ACTIVE -> PRODRUG
Name Property Type Amount Referenced Substance Defining Parameters References
Biological Half-life PHARMACOKINETIC SINGLE DOSE ADMINISTRATION

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