ZOLEDRONIC ACID ANHYDROUS

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C5H10N2O7P2
Molecular Weight	272.0896
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ZOLEDRONIC ACID ANHYDROUS

Structure Search

SMILES

OC(CN1C=CN=C1)(P(O)(O)=O)P(O)(O)=O

InChI

InChIKey=XRASPMIURGNCCH-UHFFFAOYSA-N

InChI=1S/C5H10N2O7P2/c8-5(15(9,10)11,16(12,13)14)3-7-2-1-6-4-7/h1-2,4,8H,3H2,(H2,9,10,11)(H2,12,13,14)

HIDE SMILES / InChI

Molecular Formula	C5H10N2O7P2
Molecular Weight	272.0896
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:47:01 UTC 2023` Edited by `admin` on `Fri Dec 15 15:47:01 UTC 2023`
Record UNII	70HZ18PH24
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ZOLEDRONIC ACID ANHYDROUS

Common Name

English

PHOSPHONIC ACID, (1-HYDROXY-2-(1H-IMIDAZOL-1-YL)ETHYLIDENE)BIS-

Common Name

English

ANHYDROUS ZOLEDRONIC ACID

Common Name

English

(1-HYDROXY-2-IMIDAZOL-1-YLETHYLIDENE)DIPHOSPHONIC ACID

Systematic Name

English

zoledronic acid [INN]

Common Name

English

NSC-721517

Code

English

Zoledronic acid [WHO-DD]

Common Name

English

ZOLEDRONIC ACID [MI]

Common Name

English

ZOLEDRONATE

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175579

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

WHO-ATC

M05BA08

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

FDA ORPHAN DRUG

130899

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

NCI_THESAURUS

C443

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

NDF-RT

N0000007707

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

Code System Code Type Description

FDA UNII

70HZ18PH24

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

RXCUI

1546014

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

RxNorm

EPA CompTox

DTXSID0042668

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

SMS_ID

100000091815

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

INN

7254

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

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MERCK INDEX

m11658

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

Merck Index

CHEBI

46557

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

EVMPD

SUB00176MIG

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

CAS

118072-93-8

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

NCI_THESAURUS

C80120

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

NSC

721517

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

EVMPD

SUB12624MIG

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

DRUG BANK

DB00399

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

PUBCHEM

68740

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

DAILYMED

70HZ18PH24

Created by admin on Fri Dec 15 15:47:01 UTC 2023 , Edited by admin on Fri Dec 15 15:47:01 UTC 2023

PRIMARY

Related Record Type Details


					6XC1PAD3KF

ZOLEDRONIC ACID

SOLVATE->ANHYDROUS


					6XC1PAD3KF

ZOLEDRONIC ACID

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Comments:

Binding to human plasma proteins was low (approximately 22 %) and independent of the concentration of zoledronic acid.

Interaction Type:

BINDING

Amount:


					Y1X5LD5UCA

ZOLEDRONIC ACID TRIHYDRATE

SOLVATE->ANHYDROUS


					1K9U67HDID

ZOLEDRONIC ACID HEMIPENTAHYDRATE

SALT/SOLVATE -> PARENT


					1K9U67HDID

ZOLEDRONIC ACID HEMIPENTAHYDRATE

SOLVATE->ANHYDROUS


					ARL915IH66

ZOLEDRONATE TRISODIUM

SALT/SOLVATE -> PARENT


					7D7GS1SA24

ZOLEDRONATE DISODIUM

SALT/SOLVATE -> PARENT

Related Record Type Details


					70HZ18PH24

ZOLEDRONIC ACID ANHYDROUS

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC