SUBSTANCE-K RECEPTOR

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 16:47:11 GMT 2025` Edited by `admin` on `Tue Apr 01 16:47:11 GMT 2025`
Protein Type	RECEPTOR
Protein Sub Type
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	79AAW649HW
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

SUBSTANCE-K RECEPTOR

Common Name

English

NEUROKININ A RECEPTOR

Preferred Name

English

NKNAR

Common Name

English

TAC2R

Common Name

English

NK-2 RECEPTOR

Common Name

English

TACHYKININ RECEPTOR 2

Common Name

English

SKR

Common Name

English

NK2R

Common Name

English

NK2 receptor

Common Name

English

NK-2R

Common Name

English

Code System Code Type Description

FDA UNII

79AAW649HW

Created by admin on Tue Apr 01 16:47:11 GMT 2025 , Edited by admin on Tue Apr 01 16:47:11 GMT 2025

PRIMARY

UNIPROT

P21452

Created by admin on Tue Apr 01 16:47:11 GMT 2025 , Edited by admin on Tue Apr 01 16:47:11 GMT 2025

PRIMARY

PHAROS

P21452

Created by admin on Tue Apr 01 16:47:11 GMT 2025 , Edited by admin on Tue Apr 01 16:47:11 GMT 2025

PRIMARY

From	To
1_106	1_181

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_11
N	1_19

Related Record Type Details


					JJH94R3PWB

NERATINIB

INHIBITOR->OFF-TARGET

Comments:

Neratinib concentration at 10 microM

Interaction Type:

INHIBITOR

Qualification:

Percent inhibition of specific binding

Amount:


					E35SK332MS

Burapitant

INHIBITOR->OFF-TARGET

Comments:

inositol phosphate-1 formation in CHO cells expressing human NK2

Interaction Type:

BIOASSAY (CELLULAR)

Qualification:

IC50

Amount:


					CZ3T9T146K

TALNETANT

WEAK INHIBITOR->OFF TARGET

Qualification:

Ki

Amount:


					W8A6GX6UTQ

TAK-480

INHIBITOR -> TARGET

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					G9BL4978MZ

DNK-333

INHIBITOR -> TARGET

Amount:


					XW59TYL1XH

NEPADUTANT

INHIBITOR -> TARGET

Amount:


					1H7RSQ28BJ

IBODUTANT

INHIBITOR -> TARGET

Amount:


					720U2QK8I5

SAREDUTANT

INHIBITOR -> TARGET

Comments:

Tachykinin NK2 receptor antagonist that was developed by Sanofi-Aventis for anti-depressant potential

Qualification:

IC50

Amount:


					V7M68E8XRC

UK-224671

INHIBITOR -> TARGET

Amount:


					JJH94R3PWB

NERATINIB

INHIBITOR -> TARGET


					VGDEDKUKP2

CS-003 FREE BASE

INHIBITOR -> TARGET

Amount:


					YA427LW2Y2

AVE-5883

INHIBITOR -> TARGET

Qualification:

Ki

Amount:


					DZQ7B7BPD4

FK-888

WEAK INHIBITOR->OFF TARGET

Qualification:

IC50

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Molecular Formula	CHEMICAL
MOL_WEIGHT	CHEMICAL