Fudapirine

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C34H33ClN2O2
Molecular Weight	537.091
Optical Activity	UNSPECIFIED
Defined Stereocenters	2 / 2
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of Fudapirine

Structure Search

SMILES

COC1=NC=C(C=C1[C@@H](C2=CC=CC=C2)[C@@](O)(CCN(C)C)C3=C4C=CC=CC4=CC=C3)C5=CC=C(Cl)C=C5

InChI

InChIKey=MMUCHWPQRGEHDV-ZFEZZJPFSA-N

InChI=1S/C34H33ClN2O2/c1-37(2)21-20-34(38,31-15-9-13-25-10-7-8-14-29(25)31)32(26-11-5-4-6-12-26)30-22-27(23-36-33(30)39-3)24-16-18-28(35)19-17-24/h4-19,22-23,32,38H,20-21H2,1-3H3/t32-,34-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C34H33ClN2O2
Molecular Weight	537.091
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	2 / 2
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Wed Apr 02 17:09:11 GMT 2025` Edited by `admin` on `Wed Apr 02 17:09:11 GMT 2025`
Record UNII	7X86XPE5TG
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

Sudapyridine

Preferred Name

English

Fudapirine

Official Name

English

fudapirine [INN]

Common Name

English

(?S,?R)-5-(4-Chlorophenyl)-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-pyridineethanol

Systematic Name

English

WX-081

Common Name

English

3-Pyridineethanol, 5-(4-chlorophenyl)-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-, (?S,?R)-

Systematic Name

English

Code System Code Type Description

PUBCHEM

156777270

Created by admin on Wed Apr 02 17:09:11 GMT 2025 , Edited by admin on Wed Apr 02 17:09:11 GMT 2025

PRIMARY

FDA UNII

7X86XPE5TG

Created by admin on Wed Apr 02 17:09:11 GMT 2025 , Edited by admin on Wed Apr 02 17:09:11 GMT 2025

PRIMARY

CAS

1859978-72-5

Created by admin on Wed Apr 02 17:09:11 GMT 2025 , Edited by admin on Wed Apr 02 17:09:11 GMT 2025

PRIMARY

INN

13334

Created by admin on Wed Apr 02 17:09:11 GMT 2025 , Edited by admin on Wed Apr 02 17:09:11 GMT 2025

PRIMARY

Related Record Type Details


					SEV29N8JND

POTASSIUM VOLTAGE-GATED CHANNEL SUBFAMILY H MEMBER 2

OFF TARGET->NON-INHIBITOR

Amount:


					R0EM8D5HFD

MYCOBACTERIUM TUBERCULOSIS

TARGET ORGANISM->INHIBITOR

Comments:

40 strains

Qualification:

MIC90

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					TYH2E9W452

Mycobacterium tuberculosis H37Rv

TARGET ORGANISM->INHIBITOR

Qualification:

MIC

Amount:


					65R43TUM4M

Sudapyridine fumarate

SALT/SOLVATE -> PARENT

Amount:


					JL8NG3HEW9

5-(4-Chlorophenyl)-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-pyridineethanol, (?R,?S)-

ENANTIOMER -> ENANTIOMER

Amount:


					9V87ALL3NP

5-(4-Chlorophenyl)-?-[2-(dimethylamino)ethyl]-2-methoxy-?-1-naphthalenyl-?-phenyl-3-pyridineethanol, (?R,?S)-rel-

RACEMATE -> ENANTIOMER

Amount:

Related Record Type Details


					L46VZG8VU2

Desmethyl-sudapyridine

METABOLITE LESS ACTIVE -> PARENT

Amount:

Related Record Type Details


					7X86XPE5TG

ACTIVE MOIETY

Comments:

antibacterial

Amount: