U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Substance Class Protein
Created
by admin
on Tue Apr 01 21:24:16 GMT 2025
Edited
by admin
on Tue Apr 01 21:24:16 GMT 2025
Protein Sub Type
Sequence Origin HUMAN
Sequence Type COMPLETE
Record UNII
92KA2XEZ4L
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ENDOPLASMIC RETICULUM INTERFERON STIMULATOR
Preferred Name English
STIMULATOR OF INTERFERON GENES PROTEIN
Common Name English
ERIS
Common Name English
MEDIATOR OF IRF3 ACTIVATION
Common Name English
MITA
Common Name English
STING
Common Name English
TMEM173
Common Name English
TRANSMEMBRANE PROTEIN 173
Common Name English
Code System Code Type Description
FDA UNII
92KA2XEZ4L
Created by admin on Tue Apr 01 21:24:16 GMT 2025 , Edited by admin on Tue Apr 01 21:24:16 GMT 2025
PRIMARY
UNIPROT
Q86WV6
Created by admin on Tue Apr 01 21:24:16 GMT 2025 , Edited by admin on Tue Apr 01 21:24:16 GMT 2025
PRIMARY
Related Record Type Details
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AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
AGONIST -> TARGET
Endogenous agonist synthesis stimulated by DNA in cytoplasm
Kd
AGONIST -> TARGET
AGONIST -> TARGET
STING can be strongly activated by cyclic dinucleotide 22 molecules and acts as a direct sensor for them when produced by bacteria [22, 23]. Cyclic 23 dinucleotide adenosine monophosphate (c-di-AMP) is a member of the cyclic 24 dinucleotides and acts as a pathogen-associated molecular pattern (PAMP) to induce 25 immunity when it is used in vaccine formulations [24].
Name Property Type Amount Referenced Substance Defining Parameters References
Molecular Formula CHEMICAL
MOL_WEIGHT:NUMBER(CALCULATED) CHEMICAL