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Details

Stereochemistry ACHIRAL
Molecular Formula CCl3F
Molecular Weight 137.368
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of TRICHLOROMONOFLUOROMETHANE

SMILES

FC(Cl)(Cl)Cl

InChI

InChIKey=CYRMSUTZVYGINF-UHFFFAOYSA-N
InChI=1S/CCl3F/c2-1(3,4)5

HIDE SMILES / InChI

Molecular Formula CCl3F
Molecular Weight 137.368
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Trichlorofluoromethane, also known as freon-11, was used as propellant and refrigerant. Its production was banned because of the destroying of the ozone layer and contribution to the formation of the so-called ozone hole. Today, trichlorofluoromethane is obtained during recycling processes of waste cooling devices, traded on the black market, and according to recent findings still illegally manufactured.

Approval Year

PubMed

PubMed

TitleDatePubMed
Cancer morbidity of foundry workers in Korea.
2010-12
An assessment of beclomethasone dipropionate clathrate formation in a model suspension metered dose inhaler.
2010-05-31
Evaluation of strategies for anaerobic bioremediation of high concentrations of halomethanes.
2010-03
Ab initio theoretical study of the interactions between CFCl3 and SO2.
2010-02
Vitamin B12 Deficiency due to Chlorofluorocarbon: A Case Report.
2010
Simultaneous determination of CFC-11, CFC-12 and CFC-113 in seawater samples using a purge and trap gas-chromatographic system.
2009-12-15
Influence of solvent on micellar morphologies of semifluorinated block copolymers.
2009-12
Comparison of gas-solid chromatography and MM2 force field molecular binding energies for greenhouse gases on a carbonaceous surface.
2009-10-01
Friedreich's Ataxia: from the (GAA)n repeat mediated silencing to new promising molecules for therapy.
2009-09
Cardiotoxicity of Freon among refrigeration services workers: comparative cross-sectional study.
2009-07-13
Wildlife ecological screening levels for inhalation of volatile organic chemicals.
2007-06
European emissions of HFC-365mfc, a chlorine-free substitute for the foam blowing agents HCFC-141b and CFC-11.
2007-02-15
Clinical applications of perfluorocarbon nanoparticles for molecular imaging and targeted therapeutics.
2007
Regioselective synthesis of bis(2-halo-3-pyridyl) dichalcogenides (E = S, Se and Te): directed ortho-lithiation of 2-halopyridines.
2007
9-{[3-fluoro-2-(hydroxymethyl)cyclopropylidene]methyl}adenines and -guanines. Synthesis and antiviral activity of all stereoisomers1.
2006-10-05
Application of the cell potential method to predict phase equilibria of multicomponent gas hydrate systems.
2005-04-28
A new design of groundwater sampling device and its application.
2005
Standards development of global warming gas species: methane, nitrous oxide, trichlorofluoromethane, and dichlorodifluoromethane.
2004-05-01
Historical trends in occurrence and atmospheric inputs of halogenated volatile organic compounds in untreated ground water used as a source of drinking water.
2004-04-05
Multiphoton dissociation/ionization of CHCl3 and CFCl3 at 355 nm: an experimental and theoretical study.
2004
Toxicological evaluation of dry ice expanded tobacco.
2003-11-30
Hepatotoxicity associated with overexposure to 1,1-dichloro-2,2,2-trifluoroethane (HCFC-123).
2003-02-07
Chemicals studied and evaluated in long-term carcinogenesis bioassays by both the Ramazzini Foundation and the National Toxicology Program: in tribute to Cesare Maltoni and David Rall.
2002-12
The influence of redox potential on the degradation of halogenated methanes.
2002-03
Background monitoring and long-range transport of atmospheric CFC-11 and CFC-12 at Kosan, Korea.
2001-07
PBPK modeling of canine inhalation exposures to halogenated hydrocarbons.
2001-03
Chemistry of trichlorofluoromethane: synthesis of chlorofluoromethyl phenyl sulfone and fluoromethyl phenyl sulfone and some of their reactions.
2001-02-09
Determination of perfluorobutane in rat blood by automatic headspace capillary gas chromatography and selected ion monitoring mass spectrometry.
2001-01
Occurrence of organic pollutants in recovered soil fines from construction and demolition waste.
2001
Patents
Substance Class Chemical
Created
by admin
on Mon Mar 31 17:33:46 GMT 2025
Edited
by admin
on Mon Mar 31 17:33:46 GMT 2025
Record UNII
990TYB331R
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRICHLOROMONOFLUOROMETHANE
HSDB   II   VANDF  
Systematic Name English
Trichlorofluoromethane
MART.   MI   WHO-DD  
Preferred Name English
TRICHLORFLUOMETHANE
Common Name English
TRICHLOROMONOFLUOROMETHANE [II]
Common Name English
TRICHLOROMONOFLUOROMETHANE [VANDF]
Common Name English
CHLOROFLUOROCARBON 11
Common Name English
DESFLURANE IMPURITY D [EP IMPURITY]
Common Name English
DESFLURANE IMPURITY F [EP IMPURITY]
Common Name English
Trichlorofluoromethane [WHO-DD]
Common Name English
TRICHLOROMONOFLUOROMETHANE [HSDB]
Common Name English
CFC-11
Code English
TRICHLOROFLUOROMETHANE [MART.]
Common Name English
TRICHLOROFLUOROMETHANE [MI]
Common Name English
Classification Tree Code System Code
EPA PESTICIDE CODE 13
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
CFR 21 CFR 701.30
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
CFR 21 CFR 189.191
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
Code System Code Type Description
SMS_ID
100000077271
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
HSDB
138
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
WIKIPEDIA
TRICHLOROFLUOROMETHANE
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
EVMPD
SUB16031MIG
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
MERCK INDEX
m11075
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY Merck Index
PUBCHEM
6389
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
NCI_THESAURUS
C76755
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
MESH
C005848
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
DAILYMED
990TYB331R
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
RXCUI
38578
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY RxNorm
EVMPD
SUB15605MIG
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
FDA UNII
990TYB331R
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
CHEBI
48236
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
CAS
75-69-4
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
ECHA (EC/EINECS)
200-892-3
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
ChEMBL
CHEMBL348290
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
EPA CompTox
DTXSID5021384
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
PRIMARY
NCI_THESAURUS
C45678
Created by admin on Mon Mar 31 17:33:46 GMT 2025 , Edited by admin on Mon Mar 31 17:33:46 GMT 2025
CONCEPT Industrial Aid
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PARENT -> IMPURITY
CHROMATOGRAPHIC PURITY (GC)
USP
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ACTIVE MOIETY