Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C22H30N6O |
| Molecular Weight | 394.5132 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=CC=C(O)C(CN2C(NC3CCN(CCN)CC3)=NC4=C2C=CC=C4C)=N1
InChI
InChIKey=RDQSNNMSDOHAPG-UHFFFAOYSA-N
InChI=1S/C22H30N6O/c1-15-4-3-5-19-21(15)26-22(25-17-8-11-27(12-9-17)13-10-23)28(19)14-18-20(29)7-6-16(2)24-18/h3-7,17,29H,8-14,23H2,1-2H3,(H,25,26)
| Molecular Formula | C22H30N6O |
| Molecular Weight | 394.5132 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
PubMed
| Title | Date | PubMed |
|---|---|---|
| Selection of a respiratory syncytial virus fusion inhibitor clinical candidate, part 1: improving the pharmacokinetic profile using the structure-property relationship. | 2007-09-20 |
|
| Small molecules VP-14637 and JNJ-2408068 inhibit respiratory syncytial virus fusion by similar mechanisms. | 2005-06 |
|
| Short duration aerosols of JNJ 2408068 (R170591) administered prophylactically or therapeutically protect cotton rats from experimental respiratory syncytial virus infection. | 2003-11 |
|
| Substituted benzimidazoles with nanomolar activity against respiratory syncytial virus. | 2003-11 |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Mon Mar 31 21:22:50 GMT 2025
by
admin
on
Mon Mar 31 21:22:50 GMT 2025
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| Record UNII |
AB821DL88A
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| Record Status |
Validated (UNII)
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| Record Version |
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AB821DL88A
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511013
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DTXSID50185654
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317846-22-3
Created by
admin on Mon Mar 31 21:22:50 GMT 2025 , Edited by admin on Mon Mar 31 21:22:50 GMT 2025
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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TARGET ORGANISM->INHIBITOR |
Against some lab strains. Fusion inhibitor
EC50
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| Related Record | Type | Details | ||
|---|---|---|---|---|
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ACTIVE MOIETY |
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