LETAPLIMAB

Approval Year

Substance Class	Protein Created by `admin` on `Sat Dec 16 14:26:55 UTC 2023` Edited by `admin` on `Sat Dec 16 14:26:55 UTC 2023`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG4
Sequence Origin	HUMAN
Sequence Type	COMPLETE
Record UNII	BDN84I1TFE
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

LETAPLIMAB

Official Name

English

IBI188

Code

English

Letaplimab [WHO-DD]

Common Name

English

HUMAN ANTI-CD47 MONOCLONAL ANTIBODY (IBI-188)

Common Name

English

letaplimab [INN]

Code

English

IMMUNOGLOBULIN G4 (223-PROLINE,229-ALANINE,230-ALANINE,DE-C-TERMINAL-LYSINE), ANTI-(HUMAN CD47 ANTIGEN) (HUMAN MONOCLONAL IBI188 .GAMMA.4-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL IBI188 .KAPPA.-CHAIN, DIMER

Common Name

English

IBI-188

Code

English

Code System Code Type Description

INN

11366

Created by admin on Sat Dec 16 14:26:55 UTC 2023 , Edited by admin on Sat Dec 16 14:26:55 UTC 2023

PRIMARY

NCI_THESAURUS

C157385

Created by admin on Sat Dec 16 14:26:55 UTC 2023 , Edited by admin on Sat Dec 16 14:26:55 UTC 2023

PRIMARY

FDA UNII

BDN84I1TFE

Created by admin on Sat Dec 16 14:26:55 UTC 2023 , Edited by admin on Sat Dec 16 14:26:55 UTC 2023

PRIMARY

CAS

2283356-07-8

Created by admin on Sat Dec 16 14:26:55 UTC 2023 , Edited by admin on Sat Dec 16 14:26:55 UTC 2023

PRIMARY

From	To
1_22	1_95
2_22	2_95
2_129	4_214
2_142	2_198
2_256	2_316
1_129	3_214
2_362	2_420
3_23	3_88
3_134	3_194
4_23	4_88
4_134	4_194
1_142	1_198
1_221	2_221
1_224	2_224
1_256	1_316
1_362	1_420

Glycosylation Type

MAMMALIAN

Glycosylation Link Type	Site
N	1_292
N	2_292

Related Record Type Details


					90DHW5TM9S

LEUKOCYTE SURFACE ANTIGEN CD47

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					BDN84I1TFE

LETAPLIMAB

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT:NUMBER(CALCULATED)	CHEMICAL
Molecular Formula	CHEMICAL