Caxmotabart

Approval Year

Substance Class	Protein Created by `admin` on `Wed Apr 02 20:48:26 GMT 2025` Edited by `admin` on `Wed Apr 02 20:48:26 GMT 2025`
Protein Type	MONOCLONAL ANTIBODY
Protein Sub Type	IGG1\|KAPPA
Sequence Origin	HUMANIZED MOUSE
Sequence Type	COMPLETE
Record UNII	CE2Q4UW3HW
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

Caxmotabart

Common Name

English

H-gamma1 heavy chain humanized (1-450) [VH (Homo sapiens IGHV3-66*01 (81.6%) -(IGHD) -IGHJ4*01 (100%), CDR-IMGT [8.8.13] (26-33.51-58.97-109)) (1-120) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14 (CH1 R120>K (217) (121-218), hinge 1-

Preferred Name

English

caxmotabart [INN]

Common Name

English

immunoglobulin G1-kappa, anti-[Homo sapiens ERBB2 (receptor tyrosine protein kinase erbB-2, epidermal growth factor receptor 2, EGFR2, HER2, HER-2, p185c-erbB2, NEU, CD340)], humanized monoclonal antibody, with the L-kappa light chains being fused at the

Common Name

English

Immunoglobulin G1, anti-(human epidermal growth factor receptor HER2) (human-Mus musculus monoclonal rhuMab HER2 ?1-chain), disulfide with human-Mus musculus monoclonal rhuMab HER2 ?-chain fusion protein with peptide (synthetic CaaX box-containing 11-ami

Common Name

English

Code System Code Type Description

INN

13277

Created by admin on Wed Apr 02 20:48:26 GMT 2025 , Edited by admin on Wed Apr 02 20:48:26 GMT 2025

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CAS

2930815-95-3

Created by admin on Wed Apr 02 20:48:26 GMT 2025 , Edited by admin on Wed Apr 02 20:48:26 GMT 2025

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NCI_THESAURUS

C213395

Created by admin on Wed Apr 02 20:48:26 GMT 2025 , Edited by admin on Wed Apr 02 20:48:26 GMT 2025

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FDA UNII

CE2Q4UW3HW

Created by admin on Wed Apr 02 20:48:26 GMT 2025 , Edited by admin on Wed Apr 02 20:48:26 GMT 2025

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From	To
2_223	4_214
1_223	3_214
4_134	4_194
4_23	4_88
3_134	3_194
3_23	3_88
1_232	2_232
1_229	2_229
2_370	2_428
2_264	2_324
2_147	2_203
2_22	2_96
1_370	1_428
1_264	1_324
1_147	1_203
1_22	1_96