Details
| Stereochemistry | ABSOLUTE |
| Molecular Formula | C17H20BNO5 |
| Molecular Weight | 329.155 |
| Optical Activity | UNSPECIFIED |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
OB(O)[C@H](CC1=COC2=CC=CC=C12)NC(=O)[C@@H]3C[C@H]4CC[C@@H]3O4
InChI
InChIKey=RFQDLTYXNINJON-OYNZBZHQSA-N
InChI=1S/C17H20BNO5/c20-17(13-8-11-5-6-15(13)24-11)19-16(18(21)22)7-10-9-23-14-4-2-1-3-12(10)14/h1-4,9,11,13,15-16,21-22H,5-8H2,(H,19,20)/t11-,13-,15+,16+/m1/s1
| Molecular Formula | C17H20BNO5 |
| Molecular Weight | 329.155 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ABSOLUTE |
| Additional Stereochemistry | No |
| Defined Stereocenters | 4 / 4 |
| E/Z Centers | 0 |
| Optical Activity | UNSPECIFIED |
Approval Year
Cmax
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
153 ng/mL CLINICAL TRIAL https://clinicaltrials.gov/ct2/show/results/NCT04075721 |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
M-3258 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
215 ng/mL CLINICAL TRIAL https://clinicaltrials.gov/ct2/show/results/NCT04075721 |
20 mg single, oral dose: 20 mg route of administration: Oral experiment type: SINGLE co-administered: |
M-3258 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
213 ng/mL CLINICAL TRIAL https://clinicaltrials.gov/ct2/show/results/NCT04075721 |
10 mg 2 times / week multiple, oral dose: 10 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
M-3258 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
511 ng/mL CLINICAL TRIAL https://clinicaltrials.gov/ct2/show/results/NCT04075721 |
20 mg 2 times / week multiple, oral dose: 20 mg route of administration: Oral experiment type: MULTIPLE co-administered: |
M-3258 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
AUC
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
2000 ng × h/mL CLINICAL TRIAL https://clinicaltrials.gov/ct2/show/results/NCT04075721 |
10 mg single, oral dose: 10 mg route of administration: Oral experiment type: SINGLE co-administered: |
M-3258 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
|
3300 ng × h/mL CLINICAL TRIAL https://clinicaltrials.gov/ct2/show/results/NCT04075721 |
20 mg single, oral dose: 20 mg route of administration: Oral experiment type: SINGLE co-administered: |
M-3258 plasma | Homo sapiens population: UNHEALTHY age: ADULT sex: FEMALE / MALE food status: UNKNOWN |
Funbound
| Value | Dose | Co-administered | Analyte | Population |
|---|---|---|---|---|
2.69% EXPERIMENT https://pubmed.ncbi.nlm.nih.gov/36273822/ |
M-3258 plasma | Homo sapiens population: UNKNOWN age: UNKNOWN sex: UNKNOWN food status: UNKNOWN |
| Substance Class |
Chemical
Created
by
admin
on
Edited
Wed Apr 02 00:23:04 GMT 2025
by
admin
on
Wed Apr 02 00:23:04 GMT 2025
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| Record UNII |
DYU0SZB8VA
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| Record Status |
Validated (UNII)
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138319683
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DYU0SZB8VA
Created by
admin on Wed Apr 02 00:23:04 GMT 2025 , Edited by admin on Wed Apr 02 00:23:04 GMT 2025
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