2-METHOXYIDAZOXAN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C12H14N2O3
Molecular Weight	234.2512
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of 2-METHOXYIDAZOXAN

Structure Search

SMILES

COC1(COC2=CC=CC=C2O1)C3=NCCN3

InChI

InChIKey=HQGWKNGAKBPTBX-UHFFFAOYSA-N

InChI=1S/C12H14N2O3/c1-15-12(11-13-6-7-14-11)8-16-9-4-2-3-5-10(9)17-12/h2-5H,6-8H2,1H3,(H,13,14)

HIDE SMILES / InChI

Molecular Formula	C12H14N2O3
Molecular Weight	234.2512
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Targets

Targets

Primary Target	Pharmacology	Condition	Potency
Alpha-2a adrenergic receptor 70 Target ID: CHEMBL1867 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7996470	Antagonist 2849		0.62 nM [Kd]
Alpha-2b adrenergic receptor 35 Target ID: CHEMBL1942 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7996470	Antagonist 2849		3.83 nM [Kd]
Alpha-2c adrenergic receptor 44 Target ID: CHEMBL1916 Sources: https://www.ncbi.nlm.nih.gov/pubmed/7996470	Antagonist 2849		1.78 nM [Kd]

Substance Class	Chemical Created by `admin` on `Mon Mar 31 22:07:49 GMT 2025` Edited by `admin` on `Mon Mar 31 22:07:49 GMT 2025`
Record UNII	E27LB7P0ET
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

RX-821002

Preferred Name

English

2-METHOXYIDAZOXAN

Common Name

English

1H-IMIDAZOLE, 2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-

Systematic Name

English

2-(2,3-DIHYDRO-2-METHOXY-1,4-BENZODIOXIN-2-YL)-4,5-DIHYDRO-1H-IMIDAZOLE

Systematic Name

English

2-METHOXYIDAZOXAN, (±)-

Common Name

English

Code System Code Type Description

CHEBI

73287

Created by admin on Mon Mar 31 22:07:49 GMT 2025 , Edited by admin on Mon Mar 31 22:07:49 GMT 2025

PRIMARY

CAS

102575-24-6

Created by admin on Mon Mar 31 22:07:49 GMT 2025 , Edited by admin on Mon Mar 31 22:07:49 GMT 2025

PRIMARY

FDA UNII

E27LB7P0ET

Created by admin on Mon Mar 31 22:07:49 GMT 2025 , Edited by admin on Mon Mar 31 22:07:49 GMT 2025

PRIMARY

EPA CompTox

DTXSID00907762

Created by admin on Mon Mar 31 22:07:49 GMT 2025 , Edited by admin on Mon Mar 31 22:07:49 GMT 2025

PRIMARY

PUBCHEM

108094

Created by admin on Mon Mar 31 22:07:49 GMT 2025 , Edited by admin on Mon Mar 31 22:07:49 GMT 2025

PRIMARY

Related Record Type Details


					8TX9V9C9KG

2-Methoxyidazoxan hydrobromide

SALT/SOLVATE -> PARENT

Amount:


					96WL843U8D

2-METHOXYIDAZOXAN 6,7-H-3

LABELED -> NON-LABELED

Amount:


					PZ7QL34WLU

2-METHOXYIDAZOXAN, (R)-

ENANTIOMER -> RACEMATE

Amount:


					Y154T023U0

ADENOSINE RECEPTOR A2A

TARGET -> INHIBITOR

Interaction Type:

BINDING

Qualification:

IC50

Amount:


					93V99BB37L

ALPHA-2B ADRENERGIC RECEPTOR

TARGET -> INHIBITOR

Qualification:

IC50

Amount:


					P8MXA734Y2

2-Methoxyidazoxan monohydrochloride

SALT/SOLVATE -> PARENT

Amount:


					J9XQM69PSX

2-METHOXYIDAZOXAN, (S)-

ENANTIOMER -> RACEMATE

Amount: