PERPHENAZINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C21H26ClN3OS
Molecular Weight	403.969
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PERPHENAZINE

Structure Search

SMILES

OCCN1CCN(CCCN2C3=C(SC4=C2C=C(Cl)C=C4)C=CC=C3)CC1

InChI

InChIKey=RGCVKNLCSQQDEP-UHFFFAOYSA-N

InChI=1S/C21H26ClN3OS/c22-17-6-7-21-19(16-17)25(18-4-1-2-5-20(18)27-21)9-3-8-23-10-12-24(13-11-23)14-15-26/h1-2,4-7,16,26H,3,8-15H2

HIDE SMILES / InChI

Molecular Formula	C21H26ClN3OS
Molecular Weight	403.969
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:27:42 UTC 2023` Edited by `admin` on `Fri Dec 15 16:27:42 UTC 2023`
Record UNII	FTA7XXY4EZ
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PERPHENAZINE

Official Name

English

PERPHENAZINE COMPONENT OF ETRAFON-A

Common Name

English

PIPERAZINEETHANOL, 4-(3-(2-CHLORO-10H-PHENOTHIAZIN-10-YL)PROPYL)-

Systematic Name

English

PERPHENAZINE [HSDB]

Common Name

English

4-[3-(2-Chlorophenothiazin-10-yl)propyl]-1-piperazineethanol

Systematic Name

English

TRILAFON

Brand Name

English

PERPHENAZINE [VANDF]

Common Name

English

PERPHENAZINE [USP MONOGRAPH]

Common Name

English

PERPHENAZINE [MART.]

Common Name

English

Perphenazine [WHO-DD]

Common Name

English

PERPHENAZINE MALEATE [JAN]

Common Name

English

PERPHENAZINE [JAN]

Common Name

English

NSC-150866

Code

English

PERPHENAZINE [EP MONOGRAPH]

Common Name

English

ETRAFON-A COMPONENT PERPHENAZINE

Common Name

English

perphenazine [INN]

Common Name

English

PERPHENAZINE [USP-RS]

Common Name

English

FLUPHENAZINE DIHYDROCHLORIDE IMPURITY E [EP IMPURITY]

Common Name

English

PERPHENAZINE [ORANGE BOOK]

Common Name

English

PERPHENAZINE [MI]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000175746

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

WHO-VATC

QN05AB03

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

LIVERTOX

NBK548366

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

NCI_THESAURUS

C29710

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

NDF-RT

N0000007544

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

NDF-RT

N0000007544

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

NDF-RT

N0000007544

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

WHO-ATC

N05AB03

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

Code System Code Type Description

RXCUI

8076

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

RxNorm

INN

637

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

EVMPD

SUB09736MIG

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

ChEMBL

CHEMBL567

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

EPA CompTox

DTXSID1023441

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

DRUG BANK

DB00850

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

FDA UNII

FTA7XXY4EZ

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

MESH

D010546

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

DAILYMED

FTA7XXY4EZ

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

WIKIPEDIA

PERPHENAZINE

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

NCI_THESAURUS

C29355

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

CHEBI

8028

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

DRUG CENTRAL

2113

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

NSC

150866

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

RS_ITEM_NUM

1511000

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

PUBCHEM

4748

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

SMS_ID

100000092394

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

CAS

58-39-9

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

ECHA (EC/EINECS)

200-381-5

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

MERCK INDEX

m8567

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

Merck Index

HSDB

3379

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

LACTMED

Perphenazine

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

IUPHAR

209

Created by admin on Fri Dec 15 16:27:42 UTC 2023 , Edited by admin on Fri Dec 15 16:27:42 UTC 2023

PRIMARY

Related Record Type Details


					54202V7DRJ

D(1A) DOPAMINE RECEPTOR

TARGET -> INHIBITOR

Amount:


					71099P640P

SALT/SOLVATE -> PARENT

Amount:


					7K96LZ09JI

PERPHENAZINE DIMALEATE

SALT/SOLVATE -> PARENT

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					FTA7XXY4EZ

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					LR0F81F33L

ALDEHYDE OXIDASE

METABOLIC ENZYME -> INHIBITOR

Qualification:

IC50

Amount:


					19GBD6T9L7

D(2) DOPAMINE RECEPTOR

TARGET -> INHIBITOR


					FTA7XXY4EZ

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

USP

Amount:

Related Record Type Details


					N01H72E9FG

NORPROCHLORPERAZINE

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

PLASMA


					72JU1448JM

7-HYDROXYPERPHENAZINE

METABOLITE -> PARENT


					5S6Q9MQ62M

PERPHENAZINE SULFOXIDE

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

PLASMA


					72JU1448JM

7-HYDROXYPERPHENAZINE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Qualification:

PLASMA

Related Record Type Details


					725URK91YR

DECHLORO PERPHENAZINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					ZOU145W1XL

FLUPHENAZINE HYDROCHLORIDE

PARENT -> IMPURITY

Comments:

UNSPECIFIED

Qualification:

EP


					5S6Q9MQ62M

PERPHENAZINE SULFOXIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					FTA7XXY4EZ

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC