AMILORIDE HYDROCHLORIDE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C6H8ClN7O.ClH.2H2O
Molecular Weight	302.119
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

O.O.Cl.NC(=N)NC(=O)C1=C(N)N=C(N)C(Cl)=N1

InChI

InChIKey=LTKVFMLMEYCWMK-UHFFFAOYSA-N

InChI=1S/C6H8ClN7O.ClH.2H2O/c7-2-4(9)13-3(8)1(12-2)5(15)14-6(10)11;;;/h(H4,8,9,13)(H4,10,11,14,15);1H;2*1H2

HIDE SMILES / InChI

Molecular Formula	C6H8ClN7O
Molecular Weight	229.627
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 17:23:05 UTC 2023` Edited by `admin` on `Fri Dec 15 17:23:05 UTC 2023`
Record UNII	FZJ37245UC
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

AMILORIDE HYDROCHLORIDE

Official Name

English

NSC-755847

Code

English

AMILORIDE HYDROCHLORIDE COMPONENT OF MODURETIC

Common Name

English

AMILORIDE HYDROCHLORIDE DIHYDRATE [MI]

Common Name

English

AMILORIDE HYDROCHLORIDE [USP MONOGRAPH]

Common Name

English

AMILORIDE HYDROCHLORIDE [USP-RS]

Common Name

English

AMILORIDE HYDROCHLORIDE [ORANGE BOOK]

Common Name

English

AMILORIDE HYDROCHLORIDE [EP IMPURITY]

Common Name

English

Amiloride hydrochloride dihydrate [WHO-DD]

Common Name

English

AMILORIDE HCL

Common Name

English

AMILORIDE HYDROCHLORIDE [USAN]

Common Name

English

AMILORIDE HYDROCHLORIDE COMPONENT OF HYDRO-RIDE

Common Name

English

MODURETIC COMPONENT AMILORIDE HYDROCHLORIDE

Common Name

English

AMILORIDE HYDROCHLORIDE [VANDF]

Common Name

English

PYRAZINECARBOXAMIDE, 3,5-DIAMINO-N-(AMINOIMINOMETHYL)-6-CHLORO-, MONOHYDROCHLORIDE DIHYDRATE

Common Name

English

N-Amidino-3,5-diamino-6-chloropyrazinecarboxamide monohydrochloride dihydrate

Systematic Name

English

AMILORIDE HYDROCHLORIDE [MART.]

Common Name

English

AMILORIDE HYDROCHLORIDE DIHYDRATE

Common Name

English

AMILORIDE HYDROCHLORIDE DEHYDRATE [WHO-IP]

Common Name

English

AMILORIDE HYDROCHLORIDE DIHYDRATE [EP MONOGRAPH]

Common Name

English

MIDAMOR

Brand Name

English

HYDRO-RIDE COMPONENT AMILORIDE HYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C49186

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

FDA ORPHAN DRUG

48190

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

EU-Orphan Drug

EU/3/03/147

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

NCI_THESAURUS

C582

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

Code System Code Type Description

PUBCHEM

68540

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

PRIMARY

ChEMBL

CHEMBL945

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

RXCUI

142424

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

PRIMARY

RxNorm

CHEBI

84743

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

NSC

755847

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

PRIMARY

MERCK INDEX

m1671

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

Merck Index

WHO INTERNATIONAL PHARMACOPEIA

AMILORIDE HYDROCHLORIDE

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

PRIMARY

Description: A pale yellow to greenish yellow powder; odourless or almost odourless. Solubility: Slightly soluble in water and ethanol (~750 g/l) TS; practically insoluble in ether R. Category: Diuretic. Storage: Amiloride hydrochloride should be kept in a well-closed container, protected from light. Definition: Amiloride hydrochloride contains not less than 98.0% and not more than 101.0% of C6H8ClN7O,HCl, calculated with reference to the dried substance.

EVMPD

SUB00445MIG

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

FDA UNII

FZJ37245UC

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

DAILYMED

FZJ37245UC

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

EVMPD

SUB21895

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

SMS_ID

100000088483

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

PRIMARY

EPA CompTox

DTXSID80169826

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

RS_ITEM_NUM

1019701

Created by admin on Fri Dec 15 17:23:06 UTC 2023 , Edited by admin on Fri Dec 15 17:23:06 UTC 2023

PRIMARY

DRUG BANK

DBSALT001807

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

CAS

17440-83-4

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

NCI_THESAURUS

C47390

Created by admin on Fri Dec 15 17:23:05 UTC 2023 , Edited by admin on Fri Dec 15 17:23:05 UTC 2023

PRIMARY

Related Record Type Details


					FZJ37245UC

AMILORIDE HYDROCHLORIDE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					7DZO8EB0Z3

AMILORIDE

PARENT -> SALT/SOLVATE


					FZJ37245UC

AMILORIDE HYDROCHLORIDE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

USP

Amount:


					7M458Q65S3

AMILORIDE HYDROCHLORIDE ANHYDROUS

ANHYDROUS->SOLVATE

Related Record Type Details


					E483J5G69C

3-AMINO-6-CHLORO-N-(DIAMINOMETHYLIDENE)-5-HYDROXYPYRAZINE-2-CARBOXAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					4KAT2Q9CHL

METHYL 3,5-DIAMINO-6-CHLOROPYRAZINE-2-CARBOXYLATE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					5WS823P8MP

3,5-DIAMINO-6-CHLOROPYRAZINE-2-CARBOXYLIC ACID

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					7DZO8EB0Z3

AMILORIDE

ACTIVE MOIETY