ERTAPENEM

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C22H25N3O7S
Molecular Weight	475.515
Optical Activity	UNSPECIFIED
Defined Stereocenters	6 / 6
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of ERTAPENEM

Structure Search

SMILES

[H][C@]12[C@@H](C)C(S[C@@H]3CN[C@@H](C3)C(=O)NC4=CC=CC(=C4)C(O)=O)=C(N1C(=O)[C@]2([H])[C@@H](C)O)C(O)=O

InChI

InChIKey=JUZNIMUFDBIJCM-ANEDZVCMSA-N

InChI=1S/C22H25N3O7S/c1-9-16-15(10(2)26)20(28)25(16)17(22(31)32)18(9)33-13-7-14(23-8-13)19(27)24-12-5-3-4-11(6-12)21(29)30/h3-6,9-10,13-16,23,26H,7-8H2,1-2H3,(H,24,27)(H,29,30)(H,31,32)/t9-,10-,13+,14+,15-,16-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C22H25N3O7S
Molecular Weight	475.515
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	6 / 6
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:59:28 UTC 2023` Edited by `admin` on `Fri Dec 15 15:59:28 UTC 2023`
Record UNII	G32F6EID2H
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

ERTAPENEM

Official Name

English

(4R,5S,6S)-3-(((3S,5S)-5-((M-CARBOXYPHENYL)CARBAMOYL)-3-PYRROLIDINYL)THIO)-6-((1R)-1-HYDROXYETHYL)-4-METHYL-7-OXO-1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID

Systematic Name

English

1-AZABICYCLO(3.2.0)HEPT-2-ENE-2-CARBOXYLIC ACID, 3-((5-(((3-CARBOXYPHENYL)AMINO)CARBONYL)-3-PYRROLIDINYL)THIO)-6-(1-HYDROXYETHYL)-4-METHYL-7-OXO-, (4R-(3(3S*,5S*), 4.ALPHA.,5.BETA.,6.BETA.(R*)))-

Systematic Name

English

ERTAPENEM [MI]

Common Name

English

Ertapenem [WHO-DD]

Common Name

English

ertapenem [INN]

Common Name

English

ERTAPENEM [VANDF]

Common Name

English

Classification Tree Code System Code

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000175496

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

WHO-ATC

J01DH03

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NCI_THESAURUS

C260

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

WHO-VATC

QJ01DH03

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

NDF-RT

N0000011294

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

LIVERTOX

NBK548006

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

Code System Code Type Description

FDA UNII

G32F6EID2H

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

LACTMED

Ertapenem

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

DAILYMED

G32F6EID2H

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

MESH

C446479

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

RXCUI

325642

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

RxNorm

EVMPD

SUB25388

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

DRUG CENTRAL

1046

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

MERCK INDEX

m5001

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

Merck Index

DRUG BANK

DB00303

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

HSDB

8020

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

CAS

153832-46-3

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

PUBCHEM

150610

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

CHEBI

404903

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

NCI_THESAURUS

C61752

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

SMS_ID

100000089365

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

INN

8049

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

EPA CompTox

DTXSID50165456

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

ChEMBL

CHEMBL1359

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

WIKIPEDIA

ERTAPENEM

Created by admin on Fri Dec 15 15:59:28 UTC 2023 , Edited by admin on Fri Dec 15 15:59:28 UTC 2023

PRIMARY

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STREPTOCOCCUS AGALACTIAE

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OXA-48 (Beta-lactamase)

ENZYME->SUBSTRATE

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MORAXELLA CATARRHALIS

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STAPHYLOCOCCUS AUREUS

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Amount:


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ERTAPENEM SODIUM

SALT/SOLVATE -> PARENT

Amount:


					K738E2MB3I

HAEMOPHILUS INFLUENZAE

TARGET ORGANISM->INHIBITOR

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					09PA36CT5R

KLEBSIELLA PNEUMONIAE

TARGET ORGANISM->INHIBITOR

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

LIGAND->BINDER

Interaction Type:

BINDING

Amount:


					514B9K0L10

ESCHERICHIA COLI

TARGET ORGANISM->INHIBITOR

Amount:

Related Record Type Details


					8398JTQ3VS

DE(AMIDE) ERTAPENEM

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:


					YP440V6LGX

ERTAPENEM, (BETA-LACTAM RING-OPENED)-

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR

Qualification:

URINE

Amount:

Related Record Type Details


					G32F6EID2H

ERTAPENEM

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC