METOPROLOL

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	RACEMIC
Molecular Formula	C15H25NO3
Molecular Weight	267.3639
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of METOPROLOL

Structure Search

SMILES

COCCC1=CC=C(OCC(O)CNC(C)C)C=C1

InChI

InChIKey=IUBSYMUCCVWXPE-UHFFFAOYSA-N

InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3

HIDE SMILES / InChI

Molecular Formula	C15H25NO3
Molecular Weight	267.3639
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:30:20 UTC 2023` Edited by `admin` on `Sat Dec 16 16:30:20 UTC 2023`
Record UNII	GEB06NHM23
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

METOPROLOL

Official Name

English

metoprolol [INN]

Common Name

English

(RS)-METOPROLOL

Common Name

English

METOPROLOL [HSDB]

Common Name

English

METOPROLOL SLOW RELEASE

Common Name

English

BEATROLOL

Brand Name

English

CGP-2175

Code

English

METOPROLOL [VANDF]

Common Name

English

2-PROPANOL, 1-(4-(2-METHOXYETHYL)PHENOXY)-3-((1-METHYLETHYL)AMINO)-

Systematic Name

English

SEROKEN

Brand Name

English

METOPROLOL [MART.]

Common Name

English

1-(4-(2-METHOXYETHYL)PHENOXY)-3-((1-METHYLETHYL)AMINO)-2-PROPANOL

Systematic Name

English

1-(ISOPROPYLAMINO)-3-(4-(2-METHOXYETHYL)PHENOXY)PROPAN-2-OL

Systematic Name

English

DL-METOPROLOL

Common Name

English

METOPROLOL [USAN]

Common Name

English

H-93/26

Code

English

METOPROLOL, (±)-

Common Name

English

Metoprolol [WHO-DD]

Common Name

English

METOPROLOL [MI]

Common Name

English

(±)-METOPROLOL

Common Name

English

Classification Tree Code System Code

WHO-ATC

C07FX03

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07BB52

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

LIVERTOX

NBK547984

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07BB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

FDA ORPHAN DRUG

804220

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07AB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-VATC

QC07BB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07FB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07CB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-VATC

QC07AB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07FX05

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-VATC

QC07AB52

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

NDF-RT

N0000175556

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-VATC

QC07CB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-VATC

QC07FB02

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

NDF-RT

N0000000161

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07AB52

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

NCI_THESAURUS

C29576

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

FDA ORPHAN DRUG

804320

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-VATC

QC07BB52

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

WHO-ATC

C07FB13

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

Code System Code Type Description

ECHA (EC/EINECS)

253-483-7

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

ALTERNATIVE

CAS

51384-51-1

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

WIKIPEDIA

METOPROLOL

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

DAILYMED

GEB06NHM23

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

ECHA (EC/EINECS)

257-166-4

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

EPA CompTox

DTXSID2023309

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

CAS

37350-58-6

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

SUPERSEDED

SMS_ID

100000076066

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

MESH

D008790

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

LACTMED

Metoprolol

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

ChEMBL

CHEMBL13

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

FDA UNII

GEB06NHM23

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

RXCUI

6918

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

RxNorm

DRUG BANK

DB00264

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

CHEBI

6904

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

HSDB

6531

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

IUPHAR

553

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

EVMPD

SUB14568MIG

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

MERCK INDEX

m7498

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

Merck Index

DRUG CENTRAL

1786

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

NCI_THESAURUS

C61845

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

INN

3471

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

CAS

54163-88-1

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

SUPERSEDED

PUBCHEM

4171

Created by admin on Sat Dec 16 16:30:23 UTC 2023 , Edited by admin on Sat Dec 16 16:30:23 UTC 2023

PRIMARY

Related Record Type Details


					IO1C09Z674

METOPROLOL FUMARATE

SALT/SOLVATE -> PARENT


					4A4MK4KIB5

BETA-1 ADRENERGIC RECEPTOR

TARGET -> AGONIST

Interaction Type:

SHORT-ACTING

Amount:


					W5S57Y3A5L

METOPROLOL TARTRATE

SALT/SOLVATE -> PARENT


					TH25PD4CCB

METOPROLOL SUCCINATE

SALT/SOLVATE -> PARENT


					2XX4SF4LD9

CYTOCHROME P450 2D15 (CANINE)

METABOLIC ENZYME -> SUBSTRATE

Amount:

Related Record Type Details


					9977TAV7FG

O-DEMETHYLMETOPROLOL

METABOLITE ACTIVE -> PARENT

Comments:

O-demethylmetoprolol is a pharmacologically active urinary metoprolol metabolite that has 5 to 10X less potent than metoprolol.


					Y6I8U8OX8P

METOPROLOL ACID

METABOLITE INACTIVE -> PARENT

Qualification:

URINE


					C19D0413EL

.ALPHA.-HYDROXYMETOPROLOL

METABOLITE ACTIVE -> PARENT

Comments:

Alpha-hydroxymetoprololhas 5 to 10X less potent than metoprolol.

Qualification:

URINE

Related Record Type Details


					GEB06NHM23

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				Elimination PHARMACOKINETIC Elimination PHARMACOKINETIC