TYROSINE-PROTEIN KINASE ABL1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 17:03:22 GMT 2025` Edited by `admin` on `Tue Apr 01 17:03:22 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	GS7PY5505H
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

ABELSON MURINE LEUKEMIA VIRAL ONCOGENE HOMOLOG 1

Preferred Name

English

TYROSINE-PROTEIN KINASE ABL1

Common Name

English

PROTO-ONCOGENE C-ABL

Common Name

English

JTK7

Common Name

English

ABELSON TYROSINE-PROTEIN KINASE 1

Common Name

English

ABL1

Common Name

English

P150

Common Name

English

Code System Code Type Description

UNIPROT

P00519

Created by admin on Tue Apr 01 17:03:22 GMT 2025 , Edited by admin on Tue Apr 01 17:03:22 GMT 2025

PRIMARY

FDA UNII

GS7PY5505H

Created by admin on Tue Apr 01 17:03:22 GMT 2025 , Edited by admin on Tue Apr 01 17:03:22 GMT 2025

PRIMARY

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					BKJ8M8G5HI

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2-Fluoro-N-(6-(4-methylpyridin-3-yl)benzo[d]thiazol-2-yl)cyclopropane-1-carboxamide, (1S,2S)-

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Amount:


					F41401512X

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Qualification:

Ki

Amount:


					M3X659D0FY

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INHIBITOR -> TARGET

Amount:


					RBZ1571X5H

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INHIBITOR -> TARGET


					4340891KFS

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INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_734] [1_813] [1_843] [1_851]	THREONINE PHOSPHATE	3L4WX7B1EI
AMINO ACID SUBSTITUTION	[1_114] [1_127] [1_138] [1_171] [1_184] [1_214]	TYROSINE O-PHOSPHATE	2R86C98KDX
AMINO ACID SUBSTITUTION	[1_710]	N6-ACETYLLYSINE	470AD5VY1X
AMINO ACID SUBSTITUTION	[1_49] [1_228] [1_445] [1_568] [1_658] [1_916] [1_976]	DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL