Rubravameran

Approval Year

Substance Class	Nucleic Acid Created by `admin` on `Wed Apr 02 20:39:41 GMT 2025` Edited by `admin` on `Wed Apr 02 20:39:41 GMT 2025`
Nucleic Acid Type	mRNA VACCINE
Sequence Type	COMPLETE
Record UNII	LEU6C3Q72D
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

RNA (recombinant 5?-[1,2-[m7G-(5??5?)-ppp-Gm]]-capped all cytidine?5-methylcytidine-substituted Venezuelan equine encephalitis virus nonstructural protein precursor fusion with severe acute respiratory syndrome coronavirus 2 spike glycoprotein XBB.1.5 va

Preferred Name

English

Rubravameran

Official Name

English

rubravameran [INN]

Common Name

English

self-amplifying messenger RNA (mRNA), 5'-capped, encoding Venezuelan equine encephalitis virus (VEEV; strain TC-83) RNA-dependent RNA polymerase complex (VEEV non-structural proteins 1-4 [nsP1, nsP2, nsP3 and nsP4]) and a codon-optimised receptor binding

Common Name

English

Code System Code Type Description

INN

13575

Created by admin on Wed Apr 02 20:39:41 GMT 2025 , Edited by admin on Wed Apr 02 20:39:41 GMT 2025

PRIMARY

FDA UNII

LEU6C3Q72D

Created by admin on Wed Apr 02 20:39:41 GMT 2025 , Edited by admin on Wed Apr 02 20:39:41 GMT 2025

PRIMARY

CAS

3004804-43-4

Created by admin on Wed Apr 02 20:39:41 GMT 2025 , Edited by admin on Wed Apr 02 20:39:41 GMT 2025

PRIMARY

Sugar	Site Range	Site Count
D-Ribose (RNA)	1_1-1_8602	8602 / 8602

Linkage	Site Range	Site Count
Phosphate	1_2-1_8602	8601 / 8601

Related Record Type Details


					B6L4N5Z4GH

SARS-COV2

TARGET ORGANISM->VACCINE ANTIGEN

Amount:

Related Record Type Details


					LEU6C3Q72D

Rubravameran

ACTIVE MOIETY

Amount:

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
NUCLEOTIDE SUBSTITUTION	[1_1]	5'-TERMINUS	G		5'-GUANOSINE-M-RNA-CAP-1-3'-PHOSPHATE	T0HQY09X7B