CABERGOLINE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C26H37N5O2
Molecular Weight	451.6043
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CABERGOLINE

Structure Search

SMILES

[H][C@@]12CC3=CNC4=C3C(=CC=C4)[C@@]1([H])C[C@H](CN2CC=C)C(=O)N(CCCN(C)C)C(=O)NCC

InChI

InChIKey=KORNTPPJEAJQIU-KJXAQDMKSA-N

InChI=1S/C26H37N5O2/c1-5-11-30-17-19(25(32)31(26(33)27-6-2)13-8-12-29(3)4)14-21-20-9-7-10-22-24(20)18(16-28-22)15-23(21)30/h5,7,9-10,16,19,21,23,28H,1,6,8,11-15,17H2,2-4H3,(H,27,33)/t19-,21-,23-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C26H37N5O2
Molecular Weight	451.6043
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 16:22:08 UTC 2023` Edited by `admin` on `Sat Dec 16 16:22:08 UTC 2023`
Record UNII	LL60K9J05T
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CABERGOLINE

Official Name

English

FCE-21336

Code

English

DOSTINEX

Brand Name

English

CABERGOLINE [JAN]

Common Name

English

CABERGOLINE [VANDF]

Common Name

English

VELACTIS

Brand Name

English

CABASER

Brand Name

English

Cabergoline [WHO-DD]

Common Name

English

CABERGOLINE [USP-RS]

Common Name

English

ERGOLINE-8.BETA.-CARBOXAMIDE, N-(3-(DIMETHYLAMINO)PROPYL)-N-((ETHYLAMINO)CARBONYL)-6-(2-PROPENYL)-

Systematic Name

English

CABERGOLINE [ORANGE BOOK]

Common Name

English

FCE 21336

Code

English

CABERGOLINE [USAN]

Common Name

English

1-[(6-Allylergolin-8β-yl)carbonyl]-1-[3-(dimethylamino)propyl]-3-ethylurea

Systematic Name

English

CABERGOLINE [EP MONOGRAPH]

Common Name

English

cabergoline [INN]

Common Name

English

CABERGOLINE [MI]

Common Name

English

CABERGOLINE [MART.]

Common Name

English

CABERGOLINE [USP MONOGRAPH]

Common Name

English

CABERGOLINE [EMA EPAR VETERINARY]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C66884

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

NCI_THESAURUS

C38149

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

WHO-VATC

QG02CB03

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

WHO-ATC

N04BC06

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

NDF-RT

N0000007618

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

LIVERTOX

135

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

WHO-VATC

QN04BC06

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

NDF-RT

N0000175827

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

WHO-ATC

G02CB03

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

NDF-RT

N0000007618

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

EMA VETERINARY ASSESSMENT REPORTS

VELACTIS [SUSPENDED]

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

Code System Code Type Description

ChEMBL

CHEMBL1201087

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

DRUG CENTRAL

460

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

MESH

C047047

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

WIKIPEDIA

CABERGOLINE

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

CAS

81409-90-7

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

IUPHAR

37

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

NCI_THESAURUS

C47428

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

INN

5860

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

SMS_ID

100000092143

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

USAN

II-10

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

EPA CompTox

DTXSID6022719

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

RXCUI

47579

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

RxNorm

CHEBI

3286

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

RS_ITEM_NUM

1084306

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

PUBCHEM

54746

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

LACTMED

Cabergoline

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

EVMPD

SUB06041MIG

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

DRUG BANK

DB00248

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

DAILYMED

LL60K9J05T

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

FDA UNII

LL60K9J05T

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

MERCK INDEX

m2876

Created by admin on Sat Dec 16 16:22:10 UTC 2023 , Edited by admin on Sat Dec 16 16:22:10 UTC 2023

PRIMARY

Merck Index

Related Record Type Details


					477M7SA9N9

CABERGOLINE DIPHOSPHATE

SALT/SOLVATE -> PARENT


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					19GBD6T9L7

D(2) DOPAMINE RECEPTOR

TARGET -> AGONIST


					LL60K9J05T

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

EP

Amount:


					LL60K9J05T

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (HPLC)

Qualification:

USP

Amount:

Related Record Type Details


					114UFJ65CL

N-(3-(DIMETHYLAMINO)PROPYL)-6-(2-PROPENYL)-ERGOLINE-8-CARBOXAMIDE, (8.BETA.)-

METABOLITE -> PARENT

Comments:

7% in urine

Interaction Type:

MINOR

Qualification:

URINE


					1A04W9L14A

6-ALLYL-8.BETA.-CARBOXYERGOLINE

METABOLITE -> PARENT

Comments:

41% in urine

Interaction Type:

MAJOR

Qualification:

URINE

Related Record Type Details


					1A04W9L14A

6-ALLYL-8.BETA.-CARBOXYERGOLINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					3LCV6MB85B

N8-(3-(DIMETHYLAMINO)PROPYL)-N1-ETHYL-6-(2-PROPENYL)-ERGOLINE-1,8-DICARBOXAMIDE, (8.BETA.)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					114UFJ65CL

N-(3-(DIMETHYLAMINO)PROPYL)-6-(2-PROPENYL)-ERGOLINE-8-CARBOXAMIDE, (8.BETA.)-

IMPURITY -> PARENT


					3LCV6MB85B

N8-(3-(DIMETHYLAMINO)PROPYL)-N1-ETHYL-6-(2-PROPENYL)-ERGOLINE-1,8-DICARBOXAMIDE, (8.BETA.)-

IMPURITY -> PARENT


					1A04W9L14A

6-ALLYL-8.BETA.-CARBOXYERGOLINE

IMPURITY -> PARENT


					5A8SL691O4

ERGOLINE-1,8-DICARBOXAMIDE, N8-(3-(DIMETHYLAMINO)PROPYL)-N1-ETHYL-N8-((ETHYLAMINO)CARBONYL)-6-(2-PROPENYL)-, (8.BETA.)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					114UFJ65CL

N-(3-(DIMETHYLAMINO)PROPYL)-6-(2-PROPENYL)-ERGOLINE-8-CARBOXAMIDE, (8.BETA.)-

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:

Related Record Type Details


					LL60K9J05T

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC