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Details

Stereochemistry ABSOLUTE
Molecular Formula C25H24FNO4
Molecular Weight 421.4608
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of PITAVASTATIN

SMILES

O[C@H](C[C@H](O)\C=C\C1=C(C2=CC=C(F)C=C2)C3=CC=CC=C3N=C1C4CC4)CC(O)=O

InChI

InChIKey=VGYFMXBACGZSIL-MCBHFWOFSA-N
InChI=1S/C25H24FNO4/c26-17-9-7-15(8-10-17)24-20-3-1-2-4-22(20)27-25(16-5-6-16)21(24)12-11-18(28)13-19(29)14-23(30)31/h1-4,7-12,16,18-19,28-29H,5-6,13-14H2,(H,30,31)/b12-11+/t18-,19-/m1/s1

HIDE SMILES / InChI
Molecular Formula C25H24FNO4
Molecular Weight 421.4608
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 1
Optical Activity UNSPECIFIED

Approval Year

Unknown
123738
Substance Class Chemical
Created
by admin
on Sat Dec 16 17:00:01 UTC 2023
Edited
by admin
on Sat Dec 16 17:00:01 UTC 2023
Record UNII
M5681Q5F9P
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
PITAVASTATIN
DASH   INN   MART.   MI   VANDF   WHO-DD  
INN  
Official Name English
PITAVASTATIN [MI]
Common Name English
pitavastatin [INN]
Common Name English
PITAVASTATIN [MART.]
Common Name English
Pitavastatin [WHO-DD]
Common Name English
NSC-760423
Code English
(3R,5S,6E)-7-(2-CYCLOPROPYL-4-(P-FLUOROPHENYL)-3-QUINOLYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID
Common Name English
K-924 component Pivastatin
Code English
ITAVASTATIN
Common Name English
NIKITA
Brand Name English
PITAVASTATIN [VANDF]
Common Name English
Classification Tree Code System Code
WHO-VATC QC10AA08
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
NDF-RT N0000175589
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
LIVERTOX NBK548065
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
NCI_THESAURUS C1655
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
WHO-ATC C10AA08
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
NDF-RT N0000000121
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
Code System Code Type Description
INN
7730
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
HSDB
8367
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
CHEBI
32020
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
RXCUI
861634
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY RxNorm
WIKIPEDIA
PITAVASTATIN
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
PUBCHEM
5282452
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
NCI_THESAURUS
C87751
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
DRUG BANK
DB08860
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
ChEMBL
CHEMBL1201753
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
DRUG CENTRAL
2214
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
NSC
760423
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
LACTMED
Pitavastatin
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
MESH
C108475
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
FDA UNII
M5681Q5F9P
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
CAS
147511-69-1
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
SMS_ID
100000088200
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
EVMPD
SUB21363
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
EPA CompTox
DTXSID1048384
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
MERCK INDEX
m8891
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY Merck Index
DAILYMED
M5681Q5F9P
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
IUPHAR
3035
Created by admin on Sat Dec 16 17:00:04 UTC 2023 , Edited by admin on Sat Dec 16 17:00:04 UTC 2023
PRIMARY
Related Record Type Details
ATP-BINDING CASSETTE SUB-FAMILY G MEMBER 2
TRANSPORTER -> INHIBITOR
Structure of PITAVASTATIN SODIUM
SALT/SOLVATE -> PARENT
Structure of PITAVASTATIN CALCIUM
SALT/SOLVATE -> PARENT
PLASMA PROTEIN FRACTION (HUMAN)
BINDER->LIGAND
BINDING
Structure of PITAVASTATIN CALCIUM PENTAHYDRATE
SALT/SOLVATE -> PARENT
CYTOCHROME P450 2D6
METABOLIC ENZYME -> SUBSTRATE
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A1
METABOLIC ENZYME -> SUBSTRATE
3-HYDROXY-3-METHYLGLUTARYL-COENZYME A REDUCTASE
TARGET -> INHIBITOR
Structure of PITAVASTATIN
EXCRETED UNCHANGED
AMOUNT EXCRETED
FECAL
Structure of PITAVASTATIN MAGNESIUM
SALT/SOLVATE -> PARENT
URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A3
METABOLIC ENZYME -> SUBSTRATE
MAJOR
Structure of PITAVASTATIN
EXCRETED UNCHANGED
AMOUNT EXCRETED
URINE
CYTOCHROME P450 2C9
METABOLIC ENZYME -> SUBSTRATE
Related Record Type Details
Structure of (3R,6E)-7-(2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-3-QUINOLINYL)-3-HYDROXY-5-OXO-6-HEPTENOIC ACID
METABOLITE -> PARENT
FECAL
Structure of PITAVASTATIN LACTONE
METABOLITE -> PARENT
URINE
Structure of (3R,6E)-7-(2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-3-QUINOLINYL)-3-HYDROXY-5-OXO-6-HEPTENOIC ACID
METABOLITE -> PARENT
URINE
Structure of (3R,5S,6E)-7-(2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-8-HYDROXY-3-QUINOLINYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID
METABOLITE -> PARENT
FECAL
Structure of (3R,5S,6E)-7-(2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-8-HYDROXY-3-QUINOLINYL)-3,5-DIHYDROXY-6-HEPTENOIC ACID
METABOLITE -> PARENT
MINOR
PLASMA
Structure of .BETA.-D-GLUCOPYRANURONIC ACID, 1-((3R,5S,6E)-7-(2-CYCLOPROPYL-4-(4-FLUOROPHENYL)-3-QUINOLINYL)-3,5-DIHYDROXY-6-HEPTENOATE)
METABOLITE -> PARENT
URINE
Structure of PITAVASTATIN LACTONE
METABOLITE -> PARENT
FECAL
Structure of PITAVASTATIN LACTONE
METABOLITE -> PARENT
MAJOR
PLASMA
Related Record Type Details
Structure of PITAVASTATIN
ACTIVE MOIETY
Name Property Type Amount Referenced Substance Defining Parameters References
Volume of Distribution PHARMACOKINETIC
Biological Half-life PHARMACOKINETIC
Tmax PHARMACOKINETIC ORAL ADMINISTRATION

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