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Details

Stereochemistry ABSOLUTE
Molecular Formula C24H28N2O5.ClH
Molecular Weight 460.95
Optical Activity UNSPECIFIED
Defined Stereocenters 2 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of BENAZEPRIL HYDROCHLORIDE

SMILES

Cl.CCOC(=O)[C@H](CCC1=CC=CC=C1)N[C@H]2CCC3=C(C=CC=C3)N(CC(O)=O)C2=O

InChI

InChIKey=VPSRQEHTHIMDQM-FKLPMGAJSA-N
InChI=1S/C24H28N2O5.ClH/c1-2-31-24(30)20(14-12-17-8-4-3-5-9-17)25-19-15-13-18-10-6-7-11-21(18)26(23(19)29)16-22(27)28;/h3-11,19-20,25H,2,12-16H2,1H3,(H,27,28);1H/t19-,20-;/m0./s1

HIDE SMILES / InChI
Molecular Formula C24H28N2O5
Molecular Weight 424.4895
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 2 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED
Molecular Formula ClH
Molecular Weight 36.461
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 0
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:19:37 UTC 2023
Edited
by admin
on Fri Dec 15 16:19:37 UTC 2023
Record UNII
N1SN99T69T
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
BENAZEPRIL HYDROCHLORIDE
EP   HSDB   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN  
Official Name English
BENAZEPRIL HYDROCHLORIDE [EMA EPAR VETERINARY]
Common Name English
BENAZEPRIL HYDROCHLORIDE COMPONENT OF LOTENSIN HCT
Common Name English
BENAZEPRIL HYDROCHLORIDE [JAN]
Common Name English
BENAZEPRIL HYDROCHLORIDE COMPONENT OF LOTREL
Common Name English
1H-1-BENZAZEPINE-1-ACETIC ACID, 3-((1-(ETHOXYCARBONYL)-3-PHENYLPROPYL)AMINO)-2,3,4,5-TETRAHYDRO-2-OXO-, MONOHYDROCHLORIDE, (S-(R*,R*))-
Common Name English
BENAZEPRIL HCL
Common Name English
BENAZEPRIL HYDROCHLORIDE COMPONENT CARDALIS
Common Name English
CGS-14824A HCL
Code English
BENAZEPRIL HYDROCHLORIDE [USP MONOGRAPH]
Common Name English
BENAZEPRIL HYDROCHLORIDE COMPONENT OF FORTEKOR PLUS
Common Name English
NSC-758920
Code English
(3S)-3-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid, 3-ethyl ester, monohydrochloride
Common Name English
BENAZEPRIL HYDROCHLORIDE [USAN]
Common Name English
Benazepril hydrochloride [WHO-DD]
Common Name English
CGS 14824A HCL
Code English
BENAZEPRIL HYDROCHLORIDE [USP IMPURITY]
Common Name English
CARDALIS COMPONENT BENAZEPRIL HYDROCHLORIDE
Brand Name English
BENAZEPRIL HYDROCHLORIDE [HSDB]
Common Name English
FORTEKOR PLUS COMPONENT BENAZEPRIL HYDROCHLORIDE
Brand Name English
LOTENSIN
Brand Name English
BENAZEPRIL HYDROCHLORIDE [MI]
Common Name English
LOTREL COMPONENT BENAZEPRIL HYDROCHLORIDE
Common Name English
LOTENSIN HCT COMPONENT BENAZEPRIL HYDROCHLORIDE
Common Name English
BENAZEPRIL HYDROCHLORIDE [ORANGE BOOK]
Common Name English
BENAZEPRIL HYDROCHLORIDE [EP IMPURITY]
Common Name English
BENAZEPRIL HYDROCHLORIDE [MART.]
Common Name English
BENAZEPRIL HYDROCHLORIDE [USP-RS]
Common Name English
Classification Tree Code System Code
EMA VETERINARY ASSESSMENT REPORTS FORTEKOR PLUS (AUTHORISED)
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
NCI_THESAURUS C247
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
EMA VETERINARY ASSESSMENT REPORTS CARDALIS (AUTHORIZED)
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
Code System Code Type Description
HSDB
86541-74-4
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
EVMPD
SUB13003MIG
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
ChEMBL
CHEMBL838
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
NSC
758920
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
DAILYMED
N1SN99T69T
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
SMS_ID
100000089958
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
MERCK INDEX
m2303
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY Merck Index
CAS
86541-74-4
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
RXCUI
235758
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY RxNorm
RS_ITEM_NUM
1048619
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
EPA CompTox
DTXSID9045922
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
FDA UNII
N1SN99T69T
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
USAN
Y-74
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
DRUG BANK
DBSALT000554
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
PUBCHEM
5362123
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
CHEBI
3012
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
NCI_THESAURUS
C28862
Created by admin on Fri Dec 15 16:19:37 UTC 2023 , Edited by admin on Fri Dec 15 16:19:37 UTC 2023
PRIMARY
Related Record Type Details
Structure of BENAZEPRIL HYDROCHLORIDE
BASIS OF STRENGTH->SUBSTANCE
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EP
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IMPURITY -> PARENT
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Structure of 1,1-DIMETHYLETHYL ((3S)-3-AMINO-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETATE
IMPURITY -> PARENT
Impurity F: not more than the area of the principal peak in the chromatogram obtained with reference solution (c) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-AMINO-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETIC ACID, (3S)-
IMPURITY -> PARENT
Impurity E: not more than the area of the principal peak in the chromatogram obtained with reference solution (c) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL, (R,R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRILAT
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of BENAZEPRILAT
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL HYDROCHLORIDE, (R,R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 1,1-DIMETHYLETHYL ((3S)-3-AMINO-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETATE
IMPURITY -> PARENT
For the calculation of content, multiply the peak area by 0.7
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL, (R,R)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL, (±)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL ETHYL ESTER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of ((3S)-3-(((1S)-3-CYCLOHEXYL-1-(ETHOXYCARBONYL)PROPYL)AMINO)-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETIC ACID
IMPURITY -> PARENT
Impurity D: not more than the area of the principal peak in the chromatogram obtained with reference solution (c) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL ETHYL ESTER
IMPURITY -> PARENT
Impurity G: not more than the area of the principal peak in the chromatogram obtained with reference solution (c) (0.2 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 1,1-DIMETHYLETHYL ((3S)-3-AMINO-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETATE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of BENAZEPRIL
IMPURITY -> PARENT
Impurity C: not more than 1.5 times the area of the principal peak in the chromatogram obtained with reference solution (c) (0.3 per cent)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of BENAZEPRIL ETHYL ESTER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of ((3S)-3-(((1S)-3-CYCLOHEXYL-1-(ETHOXYCARBONYL)PROPYL)AMINO)-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETIC ACID
IMPURITY -> PARENT
)
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-AMINO-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETIC ACID, (3S)-
IMPURITY -> PARENT
For the calculation of content, multiply the peak area by 0.5.
CHROMATOGRAPHIC PURITY (HPLC/UV)
EP
Structure of 3-AMINO-2-OXO-2,3,4,5-TETRAHYDRO-1H-1-BENZAZEPIN-1-YL)ACETIC ACID, (3S)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 3-(1-ETHOXYCARBONYL-3-CYCLOHEXYL-(1S)-PROPYL)AMINO-2,3,4,5-TETRAHYDRO-2-OXO-1H-1-(3S)-BENZAZEPINE)-1-ACETIC ACID MONOHYDROCHLORIDE
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of BENAZEPRILAT
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