DIMETACRINE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C20H26N2
Molecular Weight	294.4338
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of DIMETACRINE

Structure Search

SMILES

CN(C)CCCN1C2=CC=CC=C2C(C)(C)C3=C1C=CC=C3

InChI

InChIKey=RYQOGSFEJBUZBX-UHFFFAOYSA-N

InChI=1S/C20H26N2/c1-20(2)16-10-5-7-12-18(16)22(15-9-14-21(3)4)19-13-8-6-11-17(19)20/h5-8,10-13H,9,14-15H2,1-4H3

HIDE SMILES / InChI

Molecular Formula	C20H26N2
Molecular Weight	294.4338
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/6008540 | https://www.ncbi.nlm.nih.gov/pubmed/4149236 | https://www.ncbi.nlm.nih.gov/pubmed/1150371 | https://www.ncbi.nlm.nih.gov/pubmed/4463275

Dimetacrine is a tricyclic antidepressant. It has been used in the treatment of depressive states. Dimetacrine usage associates with risk of cardiovascular side effects.

CNS Activity

Approval Year

PubMed

PubMed

Title	Date	PubMed
The pharmacological studies on dimetacrine. I. Studies on the absorption, distribution and excretion of H3-labeled dimetacrine in the rat.	1970-09	5312397

Substance Class	Chemical Created by `admin` on `Mon Mar 31 17:45:28 GMT 2025` Edited by `admin` on `Mon Mar 31 17:45:28 GMT 2025`
Record UNII	O341NY501N
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

DIMETACRINE

Official Name

English

NSC-100297

Preferred Name

English

DIMETHACRINE

Common Name

English

dimetacrine [INN]

Common Name

English

DIMETACRINE [JAN]

Common Name

English

9,9-DIMETHYL-10-(3-(DIMETHYLAMINO)PROPYL)ACRIDAN

Systematic Name

English

Dimetacrine [WHO-DD]

Common Name

English

DIMETACRINE [MI]

Common Name

English

N,N,9,9-TETRAMETHYL-10(9H)-ACRIDINEPROPANAMINE

Systematic Name

English

DIMETHACRIN

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C265

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

WHO-VATC

QN06AA18

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

WHO-ATC

N06AA18

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

Code System Code Type Description

DRUG BANK

DB08996

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

PRIMARY

NSC

100297

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

PRIMARY

INN

2195

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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ChEMBL

CHEMBL1328913

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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FDA UNII

O341NY501N

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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DRUG CENTRAL

902

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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EPA CompTox

DTXSID4022941

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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MESH

C100110

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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NCI_THESAURUS

C81490

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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EVMPD

SUB07168MIG

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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CAS

4757-55-5

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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MERCK INDEX

m1117

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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Merck Index

PUBCHEM

94280

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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SMS_ID

100000082640

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

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WIKIPEDIA

Dimetacrine

Created by admin on Mon Mar 31 17:45:28 GMT 2025 , Edited by admin on Mon Mar 31 17:45:28 GMT 2025

PRIMARY

Related Record Type Details


					DVH164X0IF

DIMETACRINE BITARTRATE

SALT/SOLVATE -> PARENT

Related Record Type Details


					O341NY501N

ACTIVE MOIETY