CEPHALEXIN

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C16H17N3O4S.H2O
Molecular Weight	365.404
Optical Activity	UNSPECIFIED
Defined Stereocenters	3 / 3
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of CEPHALEXIN

Structure Search

SMILES

O.[H][C@]12SCC(C)=C(N1C(=O)[C@H]2NC(=O)[C@H](N)C3=CC=CC=C3)C(O)=O

InChI

InChIKey=AVGYWQBCYZHHPN-CYJZLJNKSA-N

InChI=1S/C16H17N3O4S.H2O/c1-8-7-24-15-11(14(21)19(15)12(8)16(22)23)18-13(20)10(17)9-5-3-2-4-6-9;/h2-6,10-11,15H,7,17H2,1H3,(H,18,20)(H,22,23);1H2/t10-,11-,15-;/m1./s1

HIDE SMILES / InChI

Molecular Formula	C16H17N3O4S
Molecular Weight	347.389
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	3 / 3
E/Z Centers	0
Optical Activity	UNSPECIFIED

Molecular Formula	H2O
Molecular Weight	18.0153
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:18:57 UTC 2023` Edited by `admin` on `Fri Dec 15 15:18:57 UTC 2023`
Record UNII	OBN7UDS42Y
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

CEPHALEXIN

Official Name

English

CEFALEXIN MONOHYDRATE

Common Name

English

66873

Code

English

7-(D-.ALPHA.-AMINO-.ALPHA.-PHENYLACETAMIDO)-3-METHYL-3-CEPHEM-4-CARBOXYLIC ACID MONOHYDRATE

Common Name

English

KEFLEX

Brand Name

English

CEPHALEXIN MONOHYDRATE [MI]

Common Name

English

CEFANEX

Brand Name

English

CEPHALEXIN MONOHYDRATE

Common Name

English

CEPHALEXIN [USP-RS]

Common Name

English

(6R,7R)-7-[(R)-2-Amino-2-phenylacetamido]-3-methyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid monohydrate

Systematic Name

English

CEPHALEXIN [USAN]

Common Name

English

CEFALEXIN MONOHYDRATE [EP IMPURITY]

Common Name

English

CEPHALEXIN [VANDF]

Common Name

English

NovoLexin

Brand Name

English

Cefalexin monohydrate [WHO-DD]

Common Name

English

CEFALEXIN MONOHYDRATE [EP MONOGRAPH]

Common Name

English

Biocef

Brand Name

English

CEPHALEXIN MONOHYDRATE [VANDF]

Common Name

English

KEFLET

Brand Name

English

CEPHALEXIN [USP MONOGRAPH]

Common Name

English

CEPHALEXIN [ORANGE BOOK]

Common Name

English

PANIXINE DISPERDOSE

Brand Name

English

LY-66873

Code

English

Classification Tree Code System Code

LIVERTOX

NBK548358

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

NCI_THESAURUS

C357

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

NDF-RT

N0000175488

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

LIVERTOX

NBK548666

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

CFR

21 CFR 520.376

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

Code System Code Type Description

IUPHAR

4832

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

SMS_ID

100000092402

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

DAILYMED

OBN7UDS42Y

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

ChEMBL

CHEMBL1727

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

MESH

D002506

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

CAS

23325-78-2

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

RXCUI

215948

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

PUBCHEM

62921

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

EVMPD

SUB06165MIG

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

RXCUI

2231

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

ALTERNATIVE

MERCK INDEX

m3244

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

Merck Index

NCI_THESAURUS

C356

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

FDA UNII

OBN7UDS42Y

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

EPA CompTox

DTXSID30945995

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

LACTMED

Cephalexin

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

DRUG BANK

DBSALT001841

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

CHEBI

3535

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

RS_ITEM_NUM

1099008

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

EVMPD

SUB01098MIG

Created by admin on Fri Dec 15 15:18:57 UTC 2023 , Edited by admin on Fri Dec 15 15:18:57 UTC 2023

PRIMARY

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BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

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Qualification:

USP

Amount:


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MULTIDRUG AND TOXIN EXTRUSION PROTEIN 1

TRANSPORTER -> SUBSTRATE


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PARENT -> SALT/SOLVATE

Amount:


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CEPHALEXIN ANHYDROUS

ANHYDROUS->SOLVATE


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TRANSPORTER -> INHIBITOR

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7-AMINODESACETOXYCEPHALOSPORANIC ACID

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PHENYLGLYCINE, D-

IMPURITY -> PARENT

Amount:


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CEPHALEXIN S-SULFOXIDE

IMPURITY -> PARENT


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PHENYLGLYCYLCEFALEXIN

IMPURITY -> PARENT

Amount:


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CEPHALEXIN R-SULFOXIDE

IMPURITY -> PARENT


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3-HYDROXY-4-METHYLTHIOPHEN-2(5H)-ONE

IMPURITY -> PARENT


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(6R,7R)-7-((R)-2-AMINO-2-PHENYLACETAMIDO)-3-ETHYL-8-OXO-5-THIA-1-AZABICYCLO(4.2.0)OCT-2-ENE-2-CARBOXYLIC ACID

IMPURITY -> PARENT


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IMPURITY -> PARENT


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IMPURITY -> PARENT


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N-PIVALOYL 7-AMINODESACETOXYCEPHALOSPORANIC ACID

IMPURITY -> PARENT

Related Record Type Details


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CEPHALEXIN ANHYDROUS

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Volume of Distribution	PHARMACOKINETIC

Biological Half-life	PHARMACOKINETIC				RENAL IMPAIRMENT PHARMACOKINETIC

Tmax	PHARMACOKINETIC

MIC	BIOLOGICAL				PATHOGEN: METHICILLIN-RESISTANT STAPHYLOCOCCI, MOST STRAINS OF ENTEROCOCCI, MOST STRAINS OF ENTEROBACTER spp., MORGANELLA MORGANII, AND PROTEUS VULGARIS SUSCEPTIBILITY: RESISTANT

Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC

MIC	BIOLOGICAL				PATHOGEN: S. AUREUS (INCLUDING PENILILLINASE-PRODUCING STRAINS), S. PNEUMONIAE, S. PYOGENES, E. COLI, H. INFLUENZAE, K. PNEUMONIAE, M. CATARRHALIS, P. MIRABILIS SUSCEPTIBILITY: SUSCEPTIBLE