Details
| Stereochemistry | ACHIRAL |
| Molecular Formula | C23H18FN7O2 |
| Molecular Weight | 443.4331 |
| Optical Activity | NONE |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Charge | 0 |
SHOW SMILES / InChI
SMILES
CC1=NC(C)=C(O1)C(=O)NC2=CC=C(F)C(=C2)C3=NN4C=C(C=NC4=N3)C5=NC=CC=C5C
InChI
InChIKey=GNVVPYCWVLCWKV-UHFFFAOYSA-N
InChI=1S/C23H18FN7O2/c1-12-5-4-8-25-19(12)15-10-26-23-29-21(30-31(23)11-15)17-9-16(6-7-18(17)24)28-22(32)20-13(2)27-14(3)33-20/h4-11H,1-3H3,(H,28,32)
| Molecular Formula | C23H18FN7O2 |
| Molecular Weight | 443.4331 |
| Charge | 0 |
| Count |
|
| Stereochemistry | ACHIRAL |
| Additional Stereochemistry | No |
| Defined Stereocenters | 0 / 0 |
| E/Z Centers | 0 |
| Optical Activity | NONE |
Approval Year
| Substance Class |
Chemical
Created
by
admin
on
Edited
Sat Dec 16 14:17:05 UTC 2023
by
admin
on
Sat Dec 16 14:17:05 UTC 2023
|
| Record UNII |
OIK6I0DA01
|
| Record Status |
Validated (UNII)
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| Record Version |
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-
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OIK6I0DA01
Created by
admin on Sat Dec 16 14:17:05 UTC 2023 , Edited by admin on Sat Dec 16 14:17:05 UTC 2023
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1799330-15-6
Created by
admin on Sat Dec 16 14:17:05 UTC 2023 , Edited by admin on Sat Dec 16 14:17:05 UTC 2023
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118162630
Created by
admin on Sat Dec 16 14:17:05 UTC 2023 , Edited by admin on Sat Dec 16 14:17:05 UTC 2023
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PRIMARY |
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|---|---|---|---|---|
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TARGET -> INHIBITOR |
Dosing at 1 mg/kg b.i.d. led to a 95% reduction of parasite burden in the liver, an efficacy equivalent to that effected by a 12 mg/kg q.d. regimen of miltefosine.
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ACTIVE MOIETY |
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