NIZATIDINE

Details

Stereochemistry	ACHIRAL
Molecular Formula	C12H21N5O2S2
Molecular Weight	331.457
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	1
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CNC(NCCSCC1=CSC(CN(C)C)=N1)=C[N+]([O-])=O

InChI

InChIKey=SGXXNSQHWDMGGP-WDZFZDKYSA-N

InChI=1S/C12H21N5O2S2/c1-13-11(6-17(18)19)14-4-5-20-8-10-9-21-12(15-10)7-16(2)3/h6,9,13-14H,4-5,7-8H2,1-3H3/b11-6-

HIDE SMILES / InChI

Molecular Formula	C12H21N5O2S2
Molecular Weight	331.457
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	1
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:11:21 UTC 2023` Edited by `admin` on `Fri Dec 15 16:11:21 UTC 2023`
Record UNII	P41PML4GHR
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NIZATIDINE

Official Name

English

NIZATIDINE [HSDB]

Common Name

English

NIZATIDINE [USP-RS]

Common Name

English

NSC-759289

Code

English

ACINON

Brand Name

English

1,1-ETHENEDIAMINE, N-(2-(((2-((DIMETHYLAMINO)METHYL)-4-THIAZOLYL)METHYL)THIO)ETHYL)-N'-METHYL-2-NITRO-

Systematic Name

English

NIZATIDINE [EP MONOGRAPH]

Common Name

English

Nizatidine [WHO-DD]

Common Name

English

nizatidine [INN]

Common Name

English

NIZATIDINE [JAN]

Common Name

English

LY 139037

Code

English

NIZATIDINE [VANDF]

Common Name

English

NIZATIDINE [USP MONOGRAPH]

Common Name

English

NIZATIDINE [ORANGE BOOK]

Common Name

English

AXID

Brand Name

English

N-(2-(((2-((DIMETHYLAMINO)METHYL)-4-THIAZOLYL)METHYL)THIO)ETHYL)-N'-METHYL-2-NITRO-1,1-ETHENE DIAMINE

Common Name

English

AXID AR

Brand Name

English

NIZATIDINE [MART.]

Common Name

English

NIZATIDINE [MI]

Common Name

English

NIZATIDINE [USP IMPURITY]

Common Name

English

NIZATIDINE [USAN]

Common Name

English

Classification Tree Code System Code

LIVERTOX

NBK548387

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

NDF-RT

N0000175784

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

WHO-VATC

QA02BA04

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

NDF-RT

N0000000151

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

NCI_THESAURUS

C29702

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

WHO-ATC

A02BA04

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

Code System Code Type Description

CHEBI

7601

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

HSDB

3574

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

LACTMED

Nizatidine

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

USAN

S-90

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

MERCK INDEX

m8017

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

Merck Index

PUBCHEM

4513

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

MESH

D016567

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

CAS

76963-41-2

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

DRUG CENTRAL

1955

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

IUPHAR

7248

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

EPA CompTox

DTXSID5023376

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

EVMPD

SUB09335MIG

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

SMS_ID

100000092426

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

DRUG BANK

DB00585

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

NCI_THESAURUS

C29295

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

RXCUI

42319

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

RxNorm

WIKIPEDIA

NIZATIDINE

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

DAILYMED

P41PML4GHR

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

RS_ITEM_NUM

1467804

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

ChEMBL

CHEMBL653

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

NSC

759289

Created by admin on Fri Dec 15 16:11:22 UTC 2023 , Edited by admin on Fri Dec 15 16:11:22 UTC 2023

PRIMARY

INN

5194

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

FDA UNII

P41PML4GHR

Created by admin on Fri Dec 15 16:11:21 UTC 2023 , Edited by admin on Fri Dec 15 16:11:21 UTC 2023

PRIMARY

Related Record Type Details


					XC55JSP2CX

HISTAMINE H2 RECEPTOR

TARGET -> INHIBITOR

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:

Related Record Type Details


					92WGS5433U

NIZATIDINE N2-OXIDE

METABOLITE -> PARENT

Comments:

About 7% of dose

Interaction Type:

MAJOR

Qualification:

URINE

Amount:


					5495DYZ7W0

NIZATIDINE SULFOXIDE

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

URINE

Amount:


					9X29GQN4HV

N2-MONODESMETHYLNIZATIDINE

METABOLITE -> PARENT

Comments:

about 5% of dose

Interaction Type:

MINOR

Qualification:

URINE

Amount:

Related Record Type Details


					DN2E59SUT9

NIZATIDINE AMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					OM0HA3681J

N-METHYL-1-(METHYLTHIO)-2-NITROETHENAMINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					5495DYZ7W0

NIZATIDINE SULFOXIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					XVT49JU72K

5,6-DIHYDRO-3-(METHYLAMINO)-2H-1,4-THIAZIN-2-ONE OXIME

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					6K6QKG6ALN

2-((DIMETHYLAMINO)METHYL)-4-THIAZOLEMETHANOL

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					HHG5BM73J9

2-(DIMETHYLAMINOMETHYL)-4-(2-AMINOETHYLTHIOMETHYL)THIAZOLE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					8QL33X2VJ2

2-(DIMETHYLAMINO)ETHANETHIOAMIDE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					CL54Q3E3T9

N'-(2-(((2-((DIMETHYLAMINO)METHYL)-4-THIAZOLYL)METHYL)THIO)ETHYL) NIZATIDINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					UX6F3U87J7

DES(N'-METHYL-2-NITRO-1,1-ETHENEDIAMINO) N'-METHYLUREIDO NIZATIDINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					GS56V5H5TY

(EZ)-N-METHYL-N'-(2-(((4-(((2-(((EZ)-1-(METHYLAMINO)-2-NITROETHENYL)AMINO)ETHYL)SULFANYL)METHYL)THIAZOL-2-YL)METHYL)SULFANYL)ETHYL)-2-NITROETHENE-1,1-DIAMINE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					X2PTM6CJ26

1,1-BIS(METHYLAMINO)-2-NITROETHENE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					P41PML4GHR

NIZATIDINE

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Volume of Distribution	PHARMACOKINETIC