BAZEDOXIFENE

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National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C30H34N2O3
Molecular Weight	470.6026
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of BAZEDOXIFENE

Structure Search

SMILES

CC1=C(N(CC2=CC=C(OCCN3CCCCCC3)C=C2)C4=CC=C(O)C=C14)C5=CC=C(O)C=C5

InChI

InChIKey=UCJGJABZCDBEDK-UHFFFAOYSA-N

InChI=1S/C30H34N2O3/c1-22-28-20-26(34)12-15-29(28)32(30(22)24-8-10-25(33)11-9-24)21-23-6-13-27(14-7-23)35-19-18-31-16-4-2-3-5-17-31/h6-15,20,33-34H,2-5,16-19,21H2,1H3

HIDE SMILES / InChI

Molecular Formula	C30H34N2O3
Molecular Weight	470.6026
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 16:03:05 UTC 2023` Edited by `admin` on `Fri Dec 15 16:03:05 UTC 2023`
Record UNII	Q16TT9C5BK
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

BAZEDOXIFENE

Official Name

English

BAZEDOXIFENE [MI]

Common Name

English

AK-R215 COMPONENT BAZEDOXIFENE

Common Name

English

AK R215 COMPONENT BAZEDOXIFENE

Common Name

English

1H-INDOL-5-OL, 1-((4-(2-(HEXAHYDRO-1H-AZEPIN-1-YL)ETHOXY)PHENYL)METHYL)-2-(4-HYDROXYPHENYL)-3-METHYL-

Systematic Name

English

BAZEDOXIFENE [VANDF]

Common Name

English

Bazedoxifene [WHO-DD]

Common Name

English

bazedoxifene [INN]

Common Name

English

BZA

Common Name

English

1-(P-(2-(HEXAHYDRO-1H-AZEPIN-1-YL)ETHOXY)BENZYL)-2-(P-HYDROXYPHENYL)-3-METHYLINDOL-5-OL

Common Name

English

BAZEDOXIFENE [EMA EPAR]

Common Name

English

Classification Tree Code System Code

LIVERTOX

NBK548475

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

WHO-ATC

G03CC07

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

NDF-RT

N0000175826

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

NCI_THESAURUS

C1821

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

WHO-VATC

QG03XC02

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

WHO-ATC

G03XC02

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

Code System Code Type Description

EPA CompTox

DTXSID70173593

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

MESH

C447119

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

INN

8168

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

DRUG BANK

DB06401

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

DAILYMED

Q16TT9C5BK

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

WIKIPEDIA

BAZEDOXIFENE

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

PUBCHEM

154257

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

SMS_ID

100000089657

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

FDA UNII

Q16TT9C5BK

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

NCI_THESAURUS

C73598

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

CAS

198481-32-2

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

EVMPD

SUB26694

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

DRUG CENTRAL

4334

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

ChEMBL

CHEMBL46740

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

RXCUI

1441386

Created by admin on Fri Dec 15 16:03:05 UTC 2023 , Edited by admin on Fri Dec 15 16:03:05 UTC 2023

PRIMARY

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					S0025AG5ZT

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A10

METABOLIC ENZYME -> SUBSTRATE


					J70472UD3D

BAZEDOXIFENE ACETATE

SALT/SOLVATE -> PARENT


					0RFO7VC96N

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A1

METABOLIC ENZYME -> SUBSTRATE


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ESTROGEN RECEPTOR

TARGET -> INHIBITOR


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MULTIDRUG RESISTANCE PROTEIN 1

TRANSPORTER -> SUBSTRATE


					S5EY2C8G0B

URIDINE DIPHOSPHATE GLUCURONOSYLTRANSFERASE 1A8

METABOLIC ENZYME -> SUBSTRATE

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METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

FECAL


					KGU18138S7

WAY-14522

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

PLASMA


					Z7UK9P79LJ

BAZEDOXIFENE-4'-GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

MINOR

Qualification:

PLASMA


					Z271JQC8WY

BAZEDOXIFENE-5-GLUCURONIDE

METABOLITE -> PARENT

Interaction Type:

MAJOR

Qualification:

PLASMA

Related Record Type Details


					Q16TT9C5BK

ACTIVE MOIETY

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC

Tmax	PHARMACOKINETIC				MULTIPLE DOSE ADMINISTRATION

Volume of Distribution	PHARMACOKINETIC