U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Details

Stereochemistry EPIMERIC
Molecular Formula C20H23N7O7
Molecular Weight 473.4393
Optical Activity UNSPECIFIED
Defined Stereocenters 1 / 2
E/Z Centers 0
Charge 0

SHOW SMILES / InChI
Structure of LEUCOVORIN

SMILES

NC1=NC(=O)C2=C(NCC(CNC3=CC=C(C=C3)C(=O)N[C@@H](CCC(O)=O)C(O)=O)N2C=O)N1

InChI

InChIKey=VVIAGPKUTFNRDU-ABLWVSNPSA-N
InChI=1S/C20H23N7O7/c21-20-25-16-15(18(32)26-20)27(9-28)12(8-23-16)7-22-11-3-1-10(2-4-11)17(31)24-13(19(33)34)5-6-14(29)30/h1-4,9,12-13,22H,5-8H2,(H,24,31)(H,29,30)(H,33,34)(H4,21,23,25,26,32)/t12?,13-/m0/s1

HIDE SMILES / InChI
Molecular Formula C20H23N7O7
Molecular Weight 473.4393
Charge 0
Count
Stereochemistry EPIMERIC
Additional Stereochemistry No
Defined Stereocenters 1 / 2
E/Z Centers 0
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:32:28 UTC 2023
Edited
by admin
on Fri Dec 15 16:32:28 UTC 2023
Record UNII
Q573I9DVLP
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
LEUCOVORIN
HSDB   VANDF  
Common Name English
N-(P-((((6RS)-2-AMINO-5-FORMYL-5,6,7,8-TETRAHYDRO-4-HYDROXY-6-PTERIDINYL)METHYL)AMINO)BENZOYL)-L-GLUTAMATE
Common Name English
FOLINIC ACID [MART.]
Common Name English
Folinic acid [WHO-DD]
Common Name English
5-FORMYLTETRAHYDROFOLIC ACID
Common Name English
FOLINIC ACID
MART.   MI   WHO-DD  
Common Name English
L-GLUTAMIC ACID, N-(4-(((2-AMINO-5-FORMYL-1,4,5,6,7,8-HEXAHYDRO-4-OXO-6-PTERIDINYL)METHYL)AMINO)BENZOYL)-
Common Name English
LEUCOVORIN [HSDB]
Common Name English
FOLINIC ACID [MI]
Common Name English
5-FORMYLTETRAHYDROFOLATE
Common Name English
LEUCOVORIN [VANDF]
Common Name English
Classification Tree Code System Code
NCI_THESAURUS C2078
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
NDF-RT N0000007151
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
NDF-RT N0000007151
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
NDF-RT N0000178369
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
FDA ORPHAN DRUG 16786
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
DSLD 187 (Number of products:13)
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
LIVERTOX 547
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
FDA ORPHAN DRUG 30588
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
NDF-RT N0000007151
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
Code System Code Type Description
CAS
58-05-9
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
HSDB
6544
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
IUPHAR
4816
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
DRUG BANK
DB00650
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
DRUG CENTRAL
1232
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
ECHA (EC/EINECS)
200-361-6
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
DAILYMED
Q573I9DVLP
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
MESH
D002955
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
NCI_THESAURUS
C71631
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
WIKIPEDIA
FOLINIC ACID
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
CHEBI
15640
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
NDF-RT
N0000175452
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY Analogs/Derivatives [Chemical/Ingredient]
EVMPD
SUB13910MIG
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
MERCK INDEX
m5519
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY Merck Index
CHEBI
57457
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
ChEMBL
CHEMBL1679
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
EPA CompTox
DTXSID0048216
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
FDA UNII
Q573I9DVLP
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
RXCUI
6313
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY RxNorm
PUBCHEM
135403648
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
SMS_ID
100000089017
Created by admin on Fri Dec 15 16:32:28 UTC 2023 , Edited by admin on Fri Dec 15 16:32:28 UTC 2023
PRIMARY
Related Record Type Details
Structure of LEUCOVORIN CALCIUM PENTAHYDRATE
SALT/SOLVATE -> PARENT
Structure of LEUCOVORIN MONOSODIUM
SALT/SOLVATE -> PARENT
Related Record Type Details
Structure of LEUCOVORIN
ACTIVE MOIETY
NIH
NCATS
PRIVACY ACT
ACCESSIBILITY
DISCLAIMER
HHS VULNERABILITY DISCLOSURE
For language access assistance, contact the NCATS Public Information Officer
National Center for Advancing Translational Sciences (NCATS),
6701 Democracy Boulevard, Bethesda MD 20892-4874 • 301-594-8966