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Details

Stereochemistry ACHIRAL
Molecular Formula C17H10F6N6O
Molecular Weight 428.2913
Optical Activity NONE
Defined Stereocenters 0 / 0
E/Z Centers 1
Charge 0

SHOW SMILES / InChI
Structure of ELTANEXOR

SMILES

NC(=O)C(=C\N1C=NC(=N1)C2=CC(=CC(=C2)C(F)(F)F)C(F)(F)F)\C3=CN=CN=C3

InChI

InChIKey=JFBAVWVBLRIWHM-AWNIVKPZSA-N
InChI=1S/C17H10F6N6O/c18-16(19,20)11-1-9(2-12(3-11)17(21,22)23)15-27-8-29(28-15)6-13(14(24)30)10-4-25-7-26-5-10/h1-8H,(H2,24,30)/b13-6+

HIDE SMILES / InChI
Molecular Formula C17H10F6N6O
Molecular Weight 428.2913
Charge 0
Count
Stereochemistry ACHIRAL
Additional Stereochemistry No
Defined Stereocenters 0 / 0
E/Z Centers 1
Optical Activity NONE

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Sat Dec 16 19:28:08 UTC 2023
Edited
by admin
on Sat Dec 16 19:28:08 UTC 2023
Record UNII
Q59IQJ9NTK
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
ELTANEXOR
USAN   INN  
Official Name English
KPT-8602
Code English
5-PYRIMIDINEACETAMIDE, .ALPHA.-((3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)METHYLENE)-, (.ALPHA.E)-
Systematic Name English
ELTANEXOR [USAN]
Common Name English
Eltanexor [WHO-DD]
Common Name English
(2E)-3-{3-[3,5-Bis(trifluoromethyl)phenyl]-1H-1,2,4-triazol-1-yl}-2-(pyrimidin-5-yl)prop-2-enamide
Systematic Name English
(E)-3-(3-(3,5-BIS(TRIFLUOROMETHYL)PHENYL)-1H-1,2,4-TRIAZOL-1-YL)-2-(PYRIMIDIN-5-YL)ACRYLAMIDE
Systematic Name English
eltanexor [INN]
Common Name English
Classification Tree Code System Code
FDA ORPHAN DRUG 857421
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
NCI_THESAURUS C129824
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
Code System Code Type Description
NCI_THESAURUS
C125193
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
CAS
1642300-52-4
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
USAN
FG-144
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
INN
10496
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
PUBCHEM
86345880
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
SMS_ID
100000183571
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
FDA UNII
Q59IQJ9NTK
Created by admin on Sat Dec 16 19:28:08 UTC 2023 , Edited by admin on Sat Dec 16 19:28:08 UTC 2023
PRIMARY
Related Record Type Details
EXPORTIN-1
TARGET -> INHIBITOR
Related Record Type Details
Structure of ELTANEXOR
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