U.S. Department of Health & Human Services Divider Arrow National Institutes of Health Divider Arrow NCATS

Approval Year

Unknown
149124
Substance Class Protein
Created
by admin
on Tue Apr 01 19:51:55 GMT 2025
Edited
by admin
on Tue Apr 01 19:51:55 GMT 2025
Protein Sub Type
Sequence Type COMPLETE
Record UNII
R6DUQ1C64H
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
MITOGEN-ACTIVATED PROTEIN KINASE 11
Common Name English
KINASE (PHOSPHORYLATING), PROTEIN P38.BETA.2 (HUMAN BRAIN)
Preferred Name English
MAP KINASE P38 BETA
Common Name English
P38B
Common Name English
MAPK 11
Common Name English
STRESS-ACTIVATED PROTEIN KINASE 2B
Common Name English
MITOGEN-ACTIVATED PROTEIN KINASE P38 BETA
Common Name English
MAP KINASE 11
Common Name English
PRKM11
Common Name English
SAPK2
Common Name English
SAPK2B
Common Name English
P38-2
Common Name English
Code System Code Type Description
EC (ENZYME CLASS)
EC 2.7.11.24
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
PRIMARY
WIKIPEDIA
MAPK11
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
PRIMARY
CAS
459597-57-0
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
CAS
479868-65-0
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
CAS
480947-97-5
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
FDA UNII
R6DUQ1C64H
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
PRIMARY
UNIPROT
Q15759
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
PRIMARY
CAS
686698-36-2
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
CAS
459597-60-5
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
CAS
1615742-71-6
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
CAS
459597-59-2
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
PHAROS
Q15759
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
PRIMARY
CAS
194499-60-0
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
PRIMARY
CAS
459597-58-1
Created by admin on Tue Apr 01 19:51:55 GMT 2025 , Edited by admin on Tue Apr 01 19:51:55 GMT 2025
ALTERNATIVE
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INHIBITOR -> TARGET
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INHIBITOR -> TARGET
Structure of TALMAPIMOD
INHIBITOR -> TARGET
Structure of LINIFANIB
INHIBITOR -> TARGET
Structure of REGORAFENIB ANHYDROUS
INHIBITOR -> TARGET
Structure of PHA-797804
INHIBITOR -> TARGET
Structure of FORETINIB
INHIBITOR -> TARGET
Structure of ADEZMAPIMOD
INHIBITOR -> TARGET
Structure of VX-702
INHIBITOR -> TARGET
Structure of SD-0006
INHIBITOR -> TARGET
Structure of TAK-715
INHIBITOR -> TARGET
Structure of DASATINIB
INHIBITOR -> TARGET
Structure of NEFLAMAPIMOD
INHIBITOR -> TARGET

Structural Modifications

Modification Type Location Site Location Type Residue Modified Extent Fragment Name Fragment Approval
AMINO ACID SUBSTITUTION [1_323] TYROSINE TYROSINE O-PHOSPHATE 2R86C98KDX
AMINO ACID SUBSTITUTION [1_180] THREONINE THREONINE PHOSPHATE 3L4WX7B1EI
AMINO ACID SUBSTITUTION [1_182] TYROSINE TYROSINE O-PHOSPHATE 2R86C98KDX
Name Property Type Amount Referenced Substance Defining Parameters References
MOL_WEIGHT:NUMBER AVERAGE(CALCULATED) CHEMICAL
NIH
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