PROGUANIL HYDROCHLORIDE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ACHIRAL
Molecular Formula	C11H16ClN5.ClH
Molecular Weight	290.192
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of PROGUANIL HYDROCHLORIDE

Structure Search

SMILES

Cl.CC(C)NC(=N)NC(=N)NC1=CC=C(Cl)C=C1

InChI

InChIKey=SARMGXPVOFNNNG-UHFFFAOYSA-N

InChI=1S/C11H16ClN5.ClH/c1-7(2)15-10(13)17-11(14)16-9-5-3-8(12)4-6-9;/h3-7H,1-2H3,(H5,13,14,15,16,17);1H

HIDE SMILES / InChI

Molecular Formula	ClH
Molecular Weight	36.461
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Molecular Formula	C11H16ClN5
Molecular Weight	253.731
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Fri Dec 15 15:08:55 UTC 2023` Edited by `admin` on `Fri Dec 15 15:08:55 UTC 2023`
Record UNII	R71Y86M0WT
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

PROGUANIL HYDROCHLORIDE

Official Name

English

GWAH7673A

Code

English

NSC-26614

Code

English

PROGUANIL HYDROCHLORIDE [MART.]

Common Name

English

GW AH7673A

Code

English

SN-12837

Code

English

CHLORGUANIDE HYDROCHLORIDE

Common Name

English

PROGUANILI HYDROCHLORIDUM [WHO-IP LATIN]

Common Name

English

PROGUANIL HYDROCHLORIDE COMPONENT OF MALARONE

Common Name

English

PALUSIL

Brand Name

English

PROGUANIL HYDROCHLORIDE [EP MONOGRAPH]

Common Name

English

Proguanil hydrochloride [WHO-DD]

Common Name

English

GUANATOL

Brand Name

English

DRINUPAL

Brand Name

English

PROGUANIL HYDROCHLORIDE COMPONENT OF MALARONE PEDIATRIC

Common Name

English

RP-3359

Code

English

M-4888

Code

English

336U50

Code

English

PROGUANIL HYDROCHLORIDE [WHO-IP]

Common Name

English

336-U-50

Code

English

PALUDRINE

Brand Name

English

PROGUANIL HYDROCHLORIDE [USP-RS]

Common Name

English

PROGUANIL HYDROCHLORIDE [ORANGE BOOK]

Common Name

English

PROGUANIL HYDROCHLORIDE [USAN]

Common Name

English

PROGUANIL HYDROCHLORIDE [JAN]

Common Name

English

MALARONE PEDIATRIC COMPONENT PROGUANIL HYDROCHLORIDE

Common Name

English

CHLOROQUANIL

Brand Name

English

NSC-12977

Code

English

GW-AH7673A

Code

English

IMIDODICARBONIMIDIC DIAMIDE, N-(4-CHLOROPHENYL)-N'-(1-METHYLETHYL)-, HYDROCHLORIDE (1:1)

Systematic Name

English

CHLORGUANIDE HYDROCHLORIDE [MI]

Common Name

English

MALARONE COMPONENT PROGUANIL HYDROCHLORIDE

Common Name

English

DIGUANYL

Brand Name

English

PROGUANIL HCL

Common Name

English

IMIDODICARBONIMIDIC DIAMIDE, N-(4-CHLOROPHENYL)-N'-(1-METHYLETHYL)-,MONOHYDROCHLORIDE

Common Name

English

PROGUANIL HYDROCHLORIDE [USP MONOGRAPH]

Common Name

English

1-(P-CHLOROPHENYL)-5-ISOPROPYLBIGUANIDE HYDROCHLORIDE

Common Name

English

CHLOROGUANIDE HYDROCHLORIDE

Common Name

English

1-(P-CHLOROPHENYL)-5-ISOPROPYLBIGUANIDE MONOHYDROCHLORIDE

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C271

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

NCI_THESAURUS

C2153

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

Code System Code Type Description

DAILYMED

R71Y86M0WT

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

NSC

26614

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

RS_ITEM_NUM

1568040

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

MERCK INDEX

m3361

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

Merck Index

EVMPD

SUB04062MIG

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

DRUG BANK

DBSALT001187

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

SMS_ID

100000091373

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

USAN

MM-06

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

CAS

637-32-1

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

NCI_THESAURUS

C47690

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

WHO INTERNATIONAL PHARMACOPEIA

PROGUANIL HYDROCHLORIDE

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

Description: A white, crystalline powder. Solubility: Slightly soluble in water, more soluble in hot water; sparingly soluble in ethanol (~750 g/l) TS. Category: Antimalarial drug.Storage: Proguanil hydrochloride should be kept in a well-closed container, protected from light. Requirements: Proguanil hydrochloride contains not less than 99.0% and not more than 101.0% of C11H16ClN5,HCl, calculated with reference tothe dried substance.

EPA CompTox

DTXSID7047776

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

ECHA (EC/EINECS)

211-283-7

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

ChEMBL

CHEMBL1377

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

PUBCHEM

12498

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

NSC

12977

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

FDA UNII

R71Y86M0WT

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

RXCUI

142428

Created by admin on Fri Dec 15 15:08:55 UTC 2023 , Edited by admin on Fri Dec 15 15:08:55 UTC 2023

PRIMARY

RxNorm

Related Record Type Details


					S61K3P7B2V

PROGUANIL

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					R71Y86M0WT

PROGUANIL HYDROCHLORIDE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

EP

Amount:


					R71Y86M0WT

PROGUANIL HYDROCHLORIDE

BASIS OF STRENGTH->SUBSTANCE

Interaction Type:

ASSAY (TITRATION)

Qualification:

USP

Amount:

Related Record Type Details


					8O3249M729

IMPURITY -> PARENT

Amount:


					64GG0L9M5R

1-(3-CHLOROPHENYL)-5-ISOPROPYLBIGUANIDE

IMPURITY -> PARENT

Amount:


					UV9L7Y722Z

ST-39008 FREE BASE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					X27G052788

1-(4-CHLOROPHENYL)-3-CYANOGUANIDINE

IMPURITY -> PARENT

Amount:


					UV9L7Y722Z

ST-39008 FREE BASE

IMPURITY -> PARENT

Comments:

at 230 nm

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:


					YM7U5A2C2G

GS-18667 FREE BASE

IMPURITY -> PARENT

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

USP

Amount:


					Z553SGH315

4-CHLOROANILINE

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					5DW6SBV5M9

1-CYANO-3-(1-METHYLETHYL)GUANIDINE

IMPURITY -> PARENT

Comments:

UNSPECIFIED

Qualification:

EP


					YM7U5A2C2G

GS-18667 FREE BASE

IMPURITY -> PARENT

Comments:

at 230 nm

Interaction Type:

CHROMATOGRAPHIC PURITY (HPLC/UV)

Qualification:

EP

Amount:

Related Record Type Details


					S61K3P7B2V

PROGUANIL

ACTIVE MOIETY