LHD-221

Details

Stereochemistry	ACHIRAL
Molecular Formula	C24H23N5OS
Molecular Weight	429.537
Optical Activity	NONE
Defined Stereocenters	0 / 0
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC(C)N1C=NC2=C1N=C(N=C2NCCC3=CC=C(O)C=C3)C4=CSC5=C4C=CC=C5

InChI

InChIKey=BGFHMYJZJZLMHW-UHFFFAOYSA-N

InChI=1S/C24H23N5OS/c1-15(2)29-14-26-21-23(25-12-11-16-7-9-17(30)10-8-16)27-22(28-24(21)29)19-13-31-20-6-4-3-5-18(19)20/h3-10,13-15,30H,11-12H2,1-2H3,(H,25,27,28)

HIDE SMILES / InChI

Molecular Formula	C24H23N5OS
Molecular Weight	429.537
Charge	0
Count

Stereochemistry	ACHIRAL
Additional Stereochemistry	No
Defined Stereocenters	0 / 0
E/Z Centers	0
Optical Activity	NONE

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 15:15:51 UTC 2023` Edited by `admin` on `Sat Dec 16 15:15:51 UTC 2023`
Record UNII	RNE1V1F9O1
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

LHD-221

Code

English

4-(2-((2-(BENZO(B)THIOPHEN-3-YL)-9-ISOPROPYL-9H-PURIN-6-YL)AMINO)ETHYL)PHENOL

Common Name

English

LFU-835

Code

English

STEMREGENIN1

Common Name

English

Code System Code Type Description

FDA UNII

RNE1V1F9O1

Created by admin on Sat Dec 16 15:15:51 UTC 2023 , Edited by admin on Sat Dec 16 15:15:51 UTC 2023

PRIMARY

EPA CompTox

DTXSID70673068

Created by admin on Sat Dec 16 15:15:51 UTC 2023 , Edited by admin on Sat Dec 16 15:15:51 UTC 2023

PRIMARY

PUBCHEM

46199207

Created by admin on Sat Dec 16 15:15:51 UTC 2023 , Edited by admin on Sat Dec 16 15:15:51 UTC 2023

PRIMARY

CAS

1227633-49-9

Created by admin on Sat Dec 16 15:15:51 UTC 2023 , Edited by admin on Sat Dec 16 15:15:51 UTC 2023

PRIMARY

Related Record Type Details


					KE8JW72ZUN

ARYL HYDROCARBON RECEPTOR

TARGET -> INHIBITOR

Amount:

Related Record Type Details


					RNE1V1F9O1

LHD-221

ACTIVE MOIETY

Comments:

LHD221, an AHR antagonist facilitates the expansion of CD34-positive hematopoietic progenitors and impedes HSPC differentiation during cytokine-driven expansion in culture.