VEBUFLOXACIN

Details

Stereochemistry	RACEMIC
Molecular Formula	C19H22FN3O3
Molecular Weight	359.3947
Optical Activity	( + / - )
Defined Stereocenters	0 / 1
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure Search

SMILES

CC1CCC2=C(N3CCN(C)CC3)C(F)=CC4=C2N1C=C(C(O)=O)C4=O

InChI

InChIKey=JATLJHBAMQKRDH-UHFFFAOYSA-N

InChI=1S/C19H22FN3O3/c1-11-3-4-12-16-13(18(24)14(19(25)26)10-23(11)16)9-15(20)17(12)22-7-5-21(2)6-8-22/h9-11H,3-8H2,1-2H3,(H,25,26)

HIDE SMILES / InChI

Molecular Formula	C19H22FN3O3
Molecular Weight	359.3947
Charge	0
Count

Stereochemistry	RACEMIC
Additional Stereochemistry	No
Defined Stereocenters	0 / 1
E/Z Centers	0
Optical Activity	( + / - )

Description
Sources: https://www.ncbi.nlm.nih.gov/pubmed/7178549 | https://www.ncbi.nlm.nih.gov/pubmed/2598310

Vebufloxacin (OPC-7241) is a nalidixic acid analog. It exhibited potent antibacterial activity against gram-positive and -negative bacteria, including Staphylococcus aureus and Pseudomonas aeruginosa.

Originator

Approval Year

PubMed

Title	Date	PubMed
Studies on antibacterial agents. I. Synthesis of substituted 6,7-dihydro-1-oxo-1H,5H-benzo[i,j]quinolizine-2-carboxylic acids.	1989-08	2598310
[Experimental studies on tissue distribution of 14C-labelled antimicrobial agent in the otorhinolaryngological field--application of macro-autoradiography].	1982-08	7178549

Substance Class	Chemical Created by `admin` on `Wed Apr 02 07:45:56 GMT 2025` Edited by `admin` on `Wed Apr 02 07:45:56 GMT 2025`
Record UNII	SXI3MP1G46
Record Status	`Validated (UNII)`
Record Version

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Name

Type

Language

VEBUFLOXACIN

Official Name

English

(±)-9-FLUORO-6,7-DIHYDRO-5-METHYL-8-(4-METHYL-1-PIPERAZINYL)-1-OXO-1H,5H-BENZO(IJ)QUINOLIZINE-2-CARBOXYLIC ACID

Preferred Name

English

VEBUFLOXACIN [JAN]

Common Name

English

vebufloxacin [INN]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C795