GLUTAMATE RECEPTOR 1

Approval Year

Substance Class	Protein Created by `admin` on `Tue Apr 01 18:25:47 GMT 2025` Edited by `admin` on `Tue Apr 01 18:25:47 GMT 2025`
Protein Sub Type
Sequence Type	COMPLETE
Record UNII	TFZ3H25BS1
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

AMPA-SELECTIVE GLUTAMATE RECEPTOR 1

Preferred Name

English

GLUTAMATE RECEPTOR 1

Common Name

English

GLUR-K1

Common Name

English

GLUTAMATE RECEPTOR IONOTROPIC, AMPA 1

Common Name

English

GLUR-A

Common Name

English

GLUH1

Common Name

English

GLUR1

Common Name

English

Code System Code Type Description

FDA UNII

TFZ3H25BS1

Created by admin on Tue Apr 01 18:25:47 GMT 2025 , Edited by admin on Tue Apr 01 18:25:47 GMT 2025

PRIMARY

UNIPROT

P42261

Created by admin on Tue Apr 01 18:25:47 GMT 2025 , Edited by admin on Tue Apr 01 18:25:47 GMT 2025

PRIMARY

From	To
1_57	1_305
1_714	1_769

Glycosylation Type

HUMAN

Glycosylation Link Type	Site
N	1_45
N	1_231
N	1_239
N	1_345
N	1_383
N	1_388

Related Record Type Details


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Comments:

AMPA-R potentiator with little agonistic effect

Interaction Type:

ALLOSTERIC ACTIVATOR


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Amount:


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INHIBITOR -> TARGET


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Amount:


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Comments:

AMPA Receptor potentiators

Interaction Type:

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Amount:


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DESFLURANE

INHIBITOR -> TARGET

Amount:


					NMA20RUS64

2-Fluoro-6-[3-fluoro-7,8-dihydro-8-oxo-7-(3-pyridinyl)-6H-pyrano[3,2-b:5,4-b?]dipyridin-9-yl]benzonitrile

INHIBITOR -> TARGET

Amount:


					CYS9AKD70P

ISOFLURANE

INHIBITOR -> TARGET

Amount:


					38LVP0K73A

SEVOFLURANE

INHIBITOR -> TARGET

Structural Modifications

Modification Type	Location Site	Location Type	Residue Modified	Extent	Fragment Name	Fragment Approval
AMINO ACID SUBSTITUTION	[1_627] [1_692] [1_831] [1_845]				DEXFOSFOSERINE	VI4F0K069V

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
MOL_WEIGHT	CHEMICAL