NALMEFENE

U.S. Department of Health & Human Services Divider Arrow

National Institutes of Health Divider Arrow

NCATS

Details

Stereochemistry	ABSOLUTE
Molecular Formula	C21H25NO3
Molecular Weight	339.4281
Optical Activity	UNSPECIFIED
Defined Stereocenters	4 / 4
E/Z Centers	0
Charge	0

SHOW SMILES / InChI

Structure of NALMEFENE

Structure Search

SMILES

[H][C@@]12OC3=C4C(C[C@H]5N(CC6CC6)CC[C@@]14[C@@]5(O)CCC2=C)=CC=C3O

InChI

InChIKey=WJBLNOPPDWQMCH-MBPVOVBZSA-N

InChI=1S/C21H25NO3/c1-12-6-7-21(24)16-10-14-4-5-15(23)18-17(14)20(21,19(12)25-18)8-9-22(16)11-13-2-3-13/h4-5,13,16,19,23-24H,1-3,6-11H2/t16-,19+,20+,21-/m1/s1

HIDE SMILES / InChI

Molecular Formula	C21H25NO3
Molecular Weight	339.4281
Charge	0
Count

Stereochemistry	ABSOLUTE
Additional Stereochemistry	No
Defined Stereocenters	4 / 4
E/Z Centers	0
Optical Activity	UNSPECIFIED

Approval Year

Substance Class	Chemical Created by `admin` on `Sat Dec 16 17:44:24 UTC 2023` Edited by `admin` on `Sat Dec 16 17:44:24 UTC 2023`
Record UNII	TOV02TDP9I
Record Status	`Validated (UNII)`
Record Version

Download

Name

Type

Language

NALMEFENE

Official Name

English

NALMEFENE [USAN]

Common Name

English

17-(Cyclopropylmethyl)-4,5α-epoxy-6-methylenemorphinan-3,14-diol

Systematic Name

English

SRD-174

Code

English

ORF-11676

Code

English

NALMEFENE [HSDB]

Common Name

English

Nalmefene [WHO-DD]

Common Name

English

ORF 11676

Code

English

ORF 1167

Code

English

JKB-121

Code

English

JF-1

Code

English

NALMEFENE [MI]

Common Name

English

nalmefene [INN]

Common Name

English

ORF-1167

Code

English

MORPHINAN-3,14-DIOL, 17-(CYCLOPROPYLMETHYL)-4,5-EPOXY-6-METHYLENE-, (5.ALPHA.)-

Systematic Name

English

NALMEFENE [VANDF]

Common Name

English

SRD174

Code

English

NALMEFENE [MART.]

Common Name

English

Classification Tree Code System Code

NCI_THESAURUS

C681

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

NDF-RT

N0000000154

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

WHO-VATC

QN07BB05

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

WHO-ATC

N07BB05

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

NDF-RT

N0000175691

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

LIVERTOX

NBK548295

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

Code System Code Type Description

MESH

C038981

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

INN

5189

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

EVMPD

SUB09139MIG

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

WIKIPEDIA

NALMEFENE

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

NCI_THESAURUS

C61855

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

USAN

T-2

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

IUPHAR

1628

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

FDA UNII

TOV02TDP9I

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

ChEMBL

CHEMBL982

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

DAILYMED

TOV02TDP9I

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

DRUG CENTRAL

1876

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

CAS

55096-26-9

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

DRUG BANK

DB06230

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

EPA CompTox

DTXSID8023347

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

PUBCHEM

5284594

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

HSDB

6761

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

SMS_ID

100000084441

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

RXCUI

31479

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

RxNorm

MERCK INDEX

m7715

Created by admin on Sat Dec 16 17:44:25 UTC 2023 , Edited by admin on Sat Dec 16 17:44:25 UTC 2023

PRIMARY

Merck Index

Related Record Type Details


					52Z0G7QVJX

NALMEFENE HYDROCHLORIDE DIHYDRATE

SALT/SOLVATE -> PARENT

Amount:


					1PE72K8X46

MU-TYPE OPIOID RECEPTOR

TARGET -> INHIBITOR


					K7K69QC05X

NALMEFENE HYDROCHLORIDE

SALT/SOLVATE -> PARENT

Amount:


					6D53G0FD0Z

PLASMA PROTEIN FRACTION (HUMAN)

BINDER->LIGAND

Interaction Type:

BINDING

Amount:


					PUO0521HZV

CYTOCHROME P450 3A4

METABOLIC ENZYME -> SUBSTRATE

Amount:


					EV0PWK6TT6

DELTA-TYPE OPIOID RECEPTOR

TARGET -> INHIBITOR

Related Record Type Details


					NLD8Y0H9J0

NALMEFENE 3-GLUCURONIDE

METABOLITE INACTIVE -> PARENT

Interaction Type:

MAJOR

Qualification:

URINE

Amount:


					9ME1830U0F

METABOLITE ACTIVE -> PARENT

Interaction Type:

MINOR

Amount:

Related Record Type Details


					TOV02TDP9I

NALMEFENE

ACTIVE MOIETY

Amount:

Name	Property Type	Amount	Referenced Substance	Defining	Parameters	References
Biological Half-life	PHARMACOKINETIC