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Details

Stereochemistry ABSOLUTE
Molecular Formula C26H35F3O6
Molecular Weight 500.5477
Optical Activity UNSPECIFIED
Defined Stereocenters 5 / 5
E/Z Centers 2
Charge 0

SHOW SMILES / InChI
Structure of TRAVOPROST

SMILES

CC(C)OC(=O)CCC\C=C/C[C@H]1[C@@H](O)C[C@@H](O)[C@@H]1\C=C\[C@@H](O)COC2=CC(=CC=C2)C(F)(F)F

InChI

InChIKey=MKPLKVHSHYCHOC-AHTXBMBWSA-N
InChI=1S/C26H35F3O6/c1-17(2)35-25(33)11-6-4-3-5-10-21-22(24(32)15-23(21)31)13-12-19(30)16-34-20-9-7-8-18(14-20)26(27,28)29/h3,5,7-9,12-14,17,19,21-24,30-32H,4,6,10-11,15-16H2,1-2H3/b5-3-,13-12+/t19-,21-,22-,23+,24-/m1/s1

HIDE SMILES / InChI
Molecular Formula C26H35F3O6
Molecular Weight 500.5477
Charge 0
Count
Stereochemistry ABSOLUTE
Additional Stereochemistry No
Defined Stereocenters 5 / 5
E/Z Centers 2
Optical Activity UNSPECIFIED

Approval Year

Unknown
86413
Substance Class Chemical
Created
by admin
on Fri Dec 15 16:36:48 UTC 2023
Edited
by admin
on Fri Dec 15 16:36:48 UTC 2023
Record UNII
WJ68R08KX9
Record Status Validated (UNII)
Record Version
  • Download
Name Type Language
TRAVOPROST
EMA EPAR   INN   JAN   MART.   MI   ORANGE BOOK   USAN   USP   USP-RS   VANDF   WHO-DD  
USAN   INN  
Official Name English
travoprost [INN]
Common Name English
TRAVOPROST [JAN]
Common Name English
TRAVOPROST [ORANGE BOOK]
Common Name English
TRAVOPROST [USP MONOGRAPH]
Common Name English
TRAVATAN
Brand Name English
NSC-760366
Code English
ISOPROPYL (Z)-7-((1R,2R,3R,5S)-3,5-DIHYDROXY-2-((1E,3R)-3-HYDROXY-4-((.ALPHA.,.ALPHA.,.ALPHA.-TRIFLUORO-M-TOLYL)OXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOATE
Systematic Name English
IZBA
Brand Name English
TRAVOPROST [MART.]
Common Name English
(1R-(1.ALPHA.(Z),2.BETA.(1E,3R*),3.ALPHA.,5.ALPHA.))-7-(3,5-DIHYDROXY-2-(3-HYDROXY-4-(3-(TRIFLUOROMETHYL)PHENOXY)-1-BUTENYL)CYCLOPENTYL)-5-HEPTENOIC ACID, 1-METHYLETHYL ESTER
Common Name English
TRAVOPROST [VANDF]
Common Name English
TRAVOPROST COMPONENT OF DUOTRAV
Brand Name English
TRAVOPROST [USAN]
Common Name English
Travoprost [WHO-DD]
Common Name English
TRAVOPROST [MI]
Common Name English
AL-6221
Code English
OTX-TP
Common Name English
DUOTRAV COMPONENT TRAVOPROST
Brand Name English
TRAVOPROST [USP-RS]
Common Name English
TRAVOPROST [EMA EPAR]
Common Name English
Classification Tree Code System Code
NDF-RT N0000175454
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
EMA ASSESSMENT REPORTS TRAVATAN (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
NCI_THESAURUS C78568
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
WHO-VATC QS01EE04
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
EMA ASSESSMENT REPORTS DUOTRAV (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
WHO-ATC S01EE04
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
EMA ASSESSMENT REPORTS IZBA (AUTHORIZED: OCULAR HYPERTENSION)
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
NDF-RT N0000007706
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
NDF-RT N0000007706
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
NCI_THESAURUS C29705
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
EMA ASSESSMENT REPORTS IZBA (AUTHORIZED: GLAUCOMA, OPEN-ANGLE)
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
NDF-RT N0000007706
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
EMA ASSESSMENT REPORTS DUOTRAV (AUTHORIZED: OCULAR HYPERTENSION)
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
EMA ASSESSMENT REPORTS TRAVATAN (AUTHORIZED: OCULAR HYPERTENSION)
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
Code System Code Type Description
USAN
JJ-93
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
INN
7775
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
WIKIPEDIA
TRAVOPROST
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
CAS
157283-68-6
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
DRUG BANK
DB00287
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
EVMPD
SUB12613MIG
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
SMS_ID
100000089312
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
LACTMED
Travoprost
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
FDA UNII
WJ68R08KX9
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
ChEMBL
CHEMBL1200799
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
DRUG CENTRAL
2716
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
DAILYMED
WJ68R08KX9
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
RS_ITEM_NUM
1673001
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
NCI_THESAURUS
C47766
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
IUPHAR
7102
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
RXCUI
283809
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY RxNorm
EPA CompTox
DTXSID80896948
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
MERCK INDEX
m11008
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY Merck Index
CHEBI
746859
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
MESH
C438103
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
PUBCHEM
5282226
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
NSC
760366
Created by admin on Fri Dec 15 16:36:48 UTC 2023 , Edited by admin on Fri Dec 15 16:36:48 UTC 2023
PRIMARY
Related Record Type Details
Structure of TRAVOPROST
BASIS OF STRENGTH->SUBSTANCE
ASSAY (HPLC)
USP
Related Record Type Details
Structure of FLUPROSTENOL, (+)-
METABOLITE ACTIVE -> PRODRUG
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Structure of TRAVOPROST 5,6-TRANS ISOMER
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
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Structure of 15-KETO TRAVOPROST
IMPURITY -> PARENT
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USP
Structure of 13,14-EPOXY TRAVOPROST
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of FLUPROSTENOL, (+)-
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Structure of 15-EPI TRAVOPROST
IMPURITY -> PARENT
CHROMATOGRAPHIC PURITY (HPLC/UV)
USP
Related Record Type Details
Structure of FLUPROSTENOL, (+)-
ACTIVE MOIETY
NIH
NCATS
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